《病理学》课程教学课件（PPT讲稿）第七章 呼吸系统疾病

DiseaseRespiratoryLu TiancaiChang BinDepartment of PathologyShihezi UniversitySchool of medicine

Respiratory Disease Lu Tiancai Chang Bin Department of Pathology Shihezi University School of medicine

肺静脉细支气管小支气管呼吸性细支气管静脉肺泡管韩泡管肺泡一肺泡囊呼吸性细支气肺泡肺泡囊肺泡囊正常肺组织模式图

正 常 肺 组 织 模 式 图

1995CornellUniversityMedicalCollege

Chronic Bronchitis(慢性支气管炎)

Chronic Bronchitis (慢性支气管炎)

1.definitionpathology:nonspecific chronic inflammation of bronchiclinical:a persistent cough with the production onsputum most days for a period of at lease3 months in at least 2 consecutive years

1. definition pathology: nonspecific chronic inflammation of bronchi clinical: a persistent cough with the production on sputum most days for a period of at lease 3 months in at least 2 consecutive years

2. Cause and Pathogenesis1)virus(病毒）2)cigarette smoke(吸烟）3)atmosphericpollution4)anaphylaxis（变态反应）impairing bronchial mucosa支气管黏膜上皮的损害

2. Cause and Pathogenesis 1) virus (病毒) 2)cigarette smoke(吸烟) 3)atmospheric pollution 4)anaphylaxis (变态反应） impairing bronchial mucosa 支气管黏膜上皮的损害

Respiratory EpitheliumMucus escalatorStructure?Nasal cavityMucusParticleCiliaMucusprodiPharynxbyEpithelialcellGobletcellDefense by means of?filtering hairs·ciliary escalator?sticky mucous

Respiratory Epithelium Structure? Mucus produced by _ Mucus escalator Defense by means of •filtering hairs •ciliary escalator •sticky mucous

3.Pathologyearly stage : the large and medium-sized bronchi)degeneration,necrosisand loss of ciliatedepitheliumofmucosa黏膜纤毛上皮变性，坏死，脱落

3.Pathology early stage : the large and medium-sized bronchi 1)degeneration, necrosis and loss of ciliated epithelium of mucosa 黏膜纤毛上皮变性，坏死，脱落

@1995Cornell UniversityMedical College@1995Cornell UniversityMedical College

2)hypertrophy，hyperplasia of mucous glands.mucous metaplasia of serous glandsincreasein the number and proportion of gobletcells.黏液腺的肥大，增生浆液腺黏液性化生杯状细胞数目和比例增加

2) hypertrophy 、 hyperplasia of mucous glands. mucous metaplasia of serous glands increase in the number and proportion of goblet cells. 黏液腺的肥大，增生 浆液腺黏液性化生 杯状细胞数目和比例增加