《肾功能检验》（英文版） Laboratory tests of renal function

Laboratory tests of renal function Junfu Huang Southwestern Hospital TMMU

Laboratory tests of renal function Junfu Huang Southwestern Hospital TMMU

Anatomy of Kidney Kidney Caly Renal artery Renal VIS Renal vein Medulla Ureter Cortex 爷ADAM

Anatomy of Kidney

米 Functions of the kidney Excretion of metabolite Waste urea, uric acid, creatinine Urine production, regulation of homeostasis, water. acid base balance Endocrine Function: renin erythropoietin, 1, 25 dihydroxycholecalciferol

Functions of the kidney Excretion of Metabolite Waste: urea, uric acid, creatinine Urine Production, regulation of homeostasis, water, acid base balance Endocrine Function: renin, erythropoietin, 1,25 - dihydroxycholecalciferol

米 Renal function tests Detect renal damage Monitor functional damage Distinguish between impairment and failure

Renal function tests Detect renal damage Monitor functional damage Distinguish between impairment and failure

米 Kidney Function A plumbers view Arterial Filter Processor Output Output Venous Urine

Kidney Function A plumbers view Filter Processor Input Arterial Output Venous Output Urine

米 How do you know it's broken? Input NO Urine! Arterial Clinical Filter symptoms Processor Output Output Venous Urine Tests

How do you know it’s broken? NO Urine! Clinical symptoms Tests Filter Processor Input Arterial Output Venous Output Urine

米 Where can it break? Input Pre-renal Arterial Renal Filter Processor Output Output Post-renal Venous Urine

Where can it break? Pre-renal Renal Post-renal Filter Processor Input Arterial Output Venous Output Urine

Laboratory tests of renal function Glomerular Function Tests Renal Tubular function Tests

Laboratory tests of renal function Glomerular Function Tests Renal Tubular Function Tests

Section 1 Investigation of Glomerular Function Renal blood flow: 1200-1400m/min Renal Plasma: 600-800ml/min 20% of plasma: glomerular filtration GFR Glomerular Filtrtion rate Concept

Section 1 Investigation of Glomerular Function Renal Blood Flow: 1200-1400ml/min Renal Plasma : 600-800ml/min 20% of plasma: glomerular filtration GFR:Glomerular Filtrtion Rate Concept

米 Renal clerance Concept Virtual volume of plasma from which the substance in question has been completely removed during a given time interval C=UVIP U urine concentrtion P: plasma con V: urine flow rate

Renal Clerance Concept Virtual volume of plasma from which the substance in question has been completely removed during a given time interval. C=UV/P U:urine concentrtion P:plasma con. V:urine flow rate