重庆医科大学：《病理学》课程教学课件（PPT讲稿）endocrine system disease_2

國走导行大导 ongqing Med山eal Uaiver Disease of Endocrine System Depart.of Pathol.CQMU

Disease of Endocrine System Depart. of Pathol. CQMU

重麦等科大学 ongging Medical University Endocrine glands (pituitary,thyroid, parathyroid,adrenal gland,pineal body, and islet) Dispersed neuroendocrine cells (thyroid C cells, gastrointestinal and bronchopulmary neuroendocrine cells

◼ Endocrine glands（pituitary, thyroid, parathyroid, adrenal gland, pineal body, and islet） ◼ Dispersed neuroendocrine cells（thyroid C cells, gastrointestinal and bronchopulmary neuroendocrine cells ）

圈重麦晋行大 gqing Med山eal Universi Purpose of Endocrine System To maintain a state of homeostasis among the various organs of the body Endocrine cells secrete hormones to regulate the activity of target organs

Purpose of Endocrine System ◼ To maintain a state of homeostasis among the various organs of the body ◼ Endocrine cells secrete hormones to regulate the activity of target organs

重麦路 hypothalamus TRH T3,T4 TSH pituitary TSH T,T4/1 thyroid Negative feedback

T3 , T4 TRH TSH hypothalamus pituitary thyroid Negative feedback

重蹇警科大骨 ongqing Medical University Abnormal activity of Endocrine System Impaired synthesis or release of hormones Abnormal interactions between hormones and their target tissues Abnormal responses of target organs to their hormones

Abnormal activity of Endocrine System ◼ Impaired synthesis or release of hormones ◼ Abnormal interactions between hormones and their target tissues ◼ Abnormal responses of target organs to their hormones

重麦等科大昂 ngging Medical Universit hyperplasia neoplasm inflammation disturbance of blood supply genitics factors biochemical consequences hyperplasia,hypertrophy or atrophy of target organs/tissue clinic consequences

hyperplasia neoplasm inflammation disturbance of blood supply genitics factors over-/underproduction of hormones biochemical consequences hyperplasia, hypertrophy or atrophy of target organs/tissue clinic consequences

重废陪科大星 gqing Med山eal Univer A proper understanding of endocrine diseases requires a careful integration of morphologic findings with biochemical measurements of the levels of hormones, their regulators,and other metabolites

A proper understanding of endocrine diseases requires a careful integration of morphologic findings with biochemical measurements of the levels of hormones, their regulators, and other metabolites

重麦路科 hongqing Medical U cavity of third mammillary optic ventricle body chiasma dura hypothalamus mater adenohypophysis neurohypophysis sphenoid bone sella anatomy turcica

anatomy adenohypophysis neurohypophysis Vestigal intermediate lobe

重蹇普科大昂 hongqing Med山cal Uaiversits Posterior pituitary Antidiuretic hormone,ADH Oxytocin,OT

Posterior pituitary ◼ Antidiuretic hormone, ADH ◼ Oxytocin, OT

重蹇等科大星 ongging Medical University Anterior pituitary ▣Acidophile cell Growth hormone,GH Prolactin,PRL ▣Basophile cell Thyroid stimulating hormone,TSH Follicle stimulating hormone,FSH Luteinizing hormone,LH Adrenocoticotrophin hormone,ACTH Lipotrophic hormone,LPH Chromophobe cell

Anterior pituitary ◼ Acidophile cell Growth hormone, GH Prolactin, PRL ◼ Basophile cell Thyroid stimulating hormone, TSH Follicle stimulating hormone, FSH Luteinizing hormone, LH Adrenocoticotrophin hormone, ACTH Lipotrophic hormone, LPH ◼ Chromophobe cell