重庆医科大学：《病理学》课程教学课件（PPT讲稿）infection diseases

重麦等科大学 nongging Medical University Infectious diseases and Parasitosis Depart.of Pathol.CQMU

Infectious diseases and Parasitosis Depart. of Pathol. CQMU

烟童走普种大 ongqing Medical University Bacillary dysentery An acute infectious disease of the intestine caused by genus Shigella Patients present with bellyache,diarrhea,blood and pus in the stools,and tenesmus enterokinesia,nervous stimulation awareness of defecation severe in infants and young children

Bacillary dysentery An acute infectious disease of the intestine caused by genus Shigella Patients present with bellyache, diarrhea, blood and pus in the stools, and tenesmus （enterokinesia↑, nervous stimulation →awareness of defecation ） severe in infants and young children

重蹇等科大学 ongging Medical University 1.Etiology and pathogenesis Shigella species Shigella dysenteriae,S.flexneri,S. sonnei and S.boydii Patients and carriers -source of infection Spread through fecal-oral transmission <1000 organism may cause an infection

1.Etiology and pathogenesis ◼ Shigella species Shigella dysenteriae , S. flexneri, S. sonnei and S. boydii ◼ Patients and carriers - source of infection ◼ Spread through fecal-oral transmission <1000 organism may cause an infection

國重走普种大 ngqing Medical University Eodotoxin-lesion in intestine Exotoxin (Shigella dysenteriae)-lesions of the bowel and CNS Bacillary culture of stool(+)-diagnosis

Eodotoxin lesion in intestine Exotoxin (Shigella dysenteriae) lesions of the bowel and CNS Bacillary culture of stool(+) – diagnosis

重麦等科大 2.Pathological changes Location large intestine,especial the sigmoid colon and rectum The affected mucosa swollen and covered with dirty exudate (pseudomembrane) pseudomembrane sloughs multiple shallow ulcers

2.Pathological changes Location large intestine, especial the sigmoid colon and rectum The affected mucosa swollen and covered with dirty exudate (pseudomembrane) pseudomembrane sloughs multiple shallow ulcers

重蹇路科大骨 ngqing Med山eal Grossly Affected mucosa present -edema -hyperemia -grey-white exudate on the mucosal surface (pseudomembrane)and small, shallow ulcers Pseudomembrane-fibrin,necrotic debris, neutrophils and bacteria

Grossly Affected mucosa present -edema -hyperemia -grey-white exudate on the mucosal surface (pseudomembrane) and small, shallow ulcers Pseudomembrane – fibrin, necrotic debris, neutrophils and bacteria

重麦等科大昂 hongqing Medical University

重唐暗科大学 hongqing Medical University

树 重麦等科大昂 nongging Medical University

重蹇普科大学 ongqing Medical University 3.Clinical types (1)Acute bacillary dysentery An acute intestine inflammation The course last 1-2 weeks Clinically sudden onset fever,abdominal pain,severe diarrhea,tenesmus,and neutrophilic leukocytosis

3.Clinical types (1)Acute bacillary dysentery An acute intestine inflammation The course last 1-2 weeks Clinically sudden onset fever, abdominal pain, severe diarrhea, tenesmus, and neutrophilic leukocytosis