重庆医科大学：《病理学》课程教学课件（PPT讲稿）Tumor

树 重麦路科大骨 honggins里Medic四Universit NEOPLASM Depart.of Pathol.CQMU

NEOPLASM Depart.of Pathol. CQMU

圈童走冬大子 ongqing Med山eal Univers Neoplasm "an abnormal tissue mass whose growth exceeds and is uncoordinated with that of adjacent normal tissue and persists after cessation of the stimuli that provoked it." -1953,willis

Neoplasm “an abnormal tissue mass whose growth exceeds and is uncoordinated with that of adjacent normal tissue and persists after cessation of the stimuli that provoked it.” -1953,willis

重麦等科大昂 Three important features in Neoplastic hyperplasia Excessive hyperplasia -loss of responsiveness to normal growth control -a certain degree of autonomy Abnormal differentiation -more or less of loss the ability to mature differentiation Persistent and progressive -be transmitted to its descendants;undergo progression heterogeneity

Three important features in Neoplastic hyperplasia Excessive hyperplasia -loss of responsiveness to normal growth control -a certain degree of autonomy Abnormal differentiation -more or less of loss the ability to mature differentiation Persistent and progressive -be transmitted to its descendants;undergo progression & heterogeneity

圈声走普什大学 ngqing Medical University Incidence of tumors Morbidity-9000,000/yr in world Occurs at all ages Mortality-7000,000/yr in world

Incidence of tumors Morbidity-9000,000/yr in world Occurs at all ages Mortality-7000,000/yr in world

重麦等科大昂 ongging Medical University The ten commonest malignant tumors in China -listed in order of mortality Respiratory tract:lung cancer nasopharyngeal carcinoma Gastrointestinal tract:esophageal cancer stomach cancer,liver cancer,large intestine cancer. Female genital:breast cancer, ovary cancer Lymphoid tissue:lymphomas Hematologic system:leukemia

The ten commonest malignant tumors in China - listed in order of mortality ⚫ Respiratory tract: lung cancer nasopharyngeal carcinoma ⚫ Gastrointestinal tract: esophageal cancer stomach cancer, liver cancer,large intestine cancer. ⚫ Female genital: breast cancer, ovary cancer ⚫ Lymphoid tissue: lymphomas ⚫ Hematologic system: leukemia

重蹇普科大星 ngging Medical University In USA lung cancer carcinoma of the breast carcinoma of the large intestine prostatic carcinoma

In USA ⚫ lung cancer ⚫ carcinoma of the breast ⚫ carcinoma of the large intestine ⚫ prostatic carcinoma

重麦路科大 ongging Medical University Nomenclature of tumor Nomenclature principle Formula:cell or tissue of cell -oma/carcinoma/sarcoma Benign tumor cell or tissue of origin 十 oma smooth muscle leiomyoma Cell of origin microscopic architecture oma serous glandular papillary papillary serous adenoma epithelium

Nomenclature of tumor Nomenclature principle Formula: cell or tissue of cell + -oma/carcinoma/sarcoma Benign tumor cell or tissue of origin + oma smooth muscle leiomyoma Cell of origin + microscopic architecture + oma serous glandular papillary papillary serous adenoma epithelium

重蹇等科大昂 nongqing Medical University Malignant epithelial tumors -carcinoma cell of origin or tissue carcinoma stratified squamous epithelium squamous cell carcinoma Malignant mesenchymal tumors-sarcoma cell of origin or tissue sarcoma smooth muscle leiomyosarcoma

Malignant tumors Malignant epithelial tumors -carcinoma cell of origin or tissue + carcinoma stratified squamous epithelium squamous cell carcinoma Malignant mesenchymal tumors -sarcoma cell of origin or tissue + sarcoma smooth muscle leiomyosarcoma

重蹇等科大星 Specially named tumors Ewin's sarcoma Kaposi's sarcoma Hodgkin lymphoma Burkitt's lymphoma

◼ Specially named tumors Ewin’s sarcoma Kaposi’s sarcoma Hodgkin lymphoma Burkitt’s lymphoma

國重走将什大学 gqing Med山eal Universi Classification Classification of tumors -importance (the first principle) -Basis (clinical biological behaviors) benign malignant borderline

Classification ◼ Classification of tumors -importance (the first principle) -Basis (clinical biological behaviors) benign malignant borderline