重庆医科大学：《病理学》课程教学课件（PPT讲稿）endocrine system disease_1

圈 重麦等科大昂 hongging Medical University Disease of Endocrine System Depart.of Pathol.CQMU

Disease of Endocrine System Depart. of Pathol. CQMU

圈重走华种大导 ongqing Med山eal Uaiver Endocrine glands (pituitary,thyroid, parathyroid,adrenal gland,pineal body, and islet) Dispersed neuroendocrine cells (thyroid C cells, gastrointestinal and bronchopulmary neuroendocrine cells

◼ Endocrine glands（pituitary, thyroid, parathyroid, adrenal gland, pineal body, and islet） ◼ Dispersed neuroendocrine cells（thyroid C cells, gastrointestinal and bronchopulmary neuroendocrine cells ）

重蹇普科大星 ongging Medical University Purpose of Endocrine System To maintain a state of homeostasis among the various organs of the body Endocrine cells secrete hormones to regulate the activity of target organs

Purpose of Endocrine System ◼ To maintain a state of homeostasis among the various organs of the body ◼ Endocrine cells secrete hormones to regulate the activity of target organs

重废暗升 gn里Mede4 hypothalamus TRH T3,T4 TsH pituitary TSH T3,T4|/↑ thyroid Negative feedback

T3 , T4 TRH TSH hypothalamus pituitary thyroid Negative feedback

重麦骑科大 ongging Medical University Abnormal activity of Endocrine System Impaired synthesis or release of hormones Abnormal interactions between hormones and their target tissues Abnormal responses of target organs to their hormones

Abnormal activity of Endocrine System ◼ Impaired synthesis or release of hormones ◼ Abnormal interactions between hormones and their target tissues ◼ Abnormal responses of target organs to their hormones

烟童走普科大导 hyperplasia neoplasm inflammation disturbance of blood supply genitics factors biochemical consequences hyperplasia,hypertrophy or atrophy of target organs/tissue clinic consequences

hyperplasia neoplasm inflammation disturbance of blood supply genitics factors over-/underproduction of hormones biochemical consequences hyperplasia, hypertrophy or atrophy of target organs/tissue clinic consequences

重麦路科大 ongging Medical University A proper understanding of endocrine diseases requires a careful integration of morphologic findings with biochemical measurements of the levels of hormones, their regulators,and other metabolites

A proper understanding of endocrine diseases requires a careful integration of morphologic findings with biochemical measurements of the levels of hormones, their regulators, and other metabolites

烟童走普行 9 gqing Med山elu cavity of third mammillary optic ventricle body chiasma dura hypothalamus mater adenohypophysis neurohypophysis sphenoid bone sella anatomy turcica

anatomy adenohypophysis neurohypophysis Vestigal intermediate lobe

重麦等科大学 ongging Medical University Posterior pituitary Antidiuretic hormone,ADH ■Oxytocin,OT

Posterior pituitary ◼ Antidiuretic hormone, ADH ◼ Oxytocin, OT

重魔陪科大骨 Anterior pituitary ·Acidophile cell Growth hormone,GH Prolactin,PRL ■Basophile cell Thyroid stimulating hormone,TSH Follicle stimulating hormone,FSH Luteinizing hormone,LH Adrenocoticotrophin hormone,ACTH Lipotrophic hormone,LPH Chromophobe cell

Anterior pituitary ◼ Acidophile cell Growth hormone, GH Prolactin, PRL ◼ Basophile cell Thyroid stimulating hormone, TSH Follicle stimulating hormone, FSH Luteinizing hormone, LH Adrenocoticotrophin hormone, ACTH Lipotrophic hormone, LPH ◼ Chromophobe cell