重庆医科大学：《病理学》课程教学课件（PPT讲稿）alimentary system disease

圈重走背种大号 ongqins里Med山eal Univers DISEASE of DIGESTIVE SYSTEM Depart.of Pathol.CQMU

DISEASE of DIGESTIVE SYSTEM Depart. of Pathol.CQMU

重麦路科大 ongging Medical University GASTRITIS Acute gastritis 1.Conception:It is an acute mucosal inflammatory process,usually of a transient nature.According to causes and clinical represents,the disorder can be classified: acute irritated gastritis, acute hemorrhagic gastritis corrosive gastritis and acute infective gastritis

GASTRITIS Acute gastritis 1.Conception：It is an acute mucosal inflammatory process, usually of a transient nature. According to causes and clinical represents, the disorder can be classified： acute irritated gastritis, acute hemorrhagic gastritis , corrosive gastritis and acute infective gastritis

重废陪科大学 ongqing Medical University 2.Etiology and pathology .Heavy use of nonsteroidal anti-inflammatory drugs (NSAIDs),particularly aspirin .Excessive alcohol consumption .Treatment with cancer chemotherapeutic drugs .Systemic infections (e.g.,salmonellosis) .Severe stress (e.g.,trauma,burns,surgery) .Ischemia and shock .Suicide attempts with acids and alkali .Mechanical trauma (e.g.,nasogastric intubation) .After distal gastrectomy with reflux of bilious material

2.Etiology and pathology •Heavy use of nonsteroidal anti-inflammatory drugs (NSAIDs) , particularly aspirin •Excessive alcohol consumption •Treatment with cancer chemotherapeutic drugs •Systemic infections (e.g., salmonellosis) •Severe stress (e.g., trauma, burns, surgery) •Ischemia and shock •Suicide attempts with acids and alkali •Mechanical trauma (e.g., nasogastric intubation) •After distal gastrectomy with reflux of bilious material

圈 重蹇等科大学 ongging Medical University 3.types acute irritated gastritis acute hemorrhagic gastritis corrosive gastritis acute infective gastritis

3.types acute irritated gastritis acute hemorrhagic gastritis corrosive gastritis acute infective gastritis

圈重麦普升大 ongqing Medical University 4.Morphology with neutrophil reaction in the superficial layers of the mucosa

4.Morphology with neutrophil reaction in the superficial layers of the mucosa

重蹇等科大学 ngginMed由ical Universi Chronic gastritis Chronic gastritis,a common disease,is defined as the presence of chronic mucosal inflammatory changes leading to ●mucosal atrophy and epithelial metaplasia

Chronic gastritis Chronic gastritis, a common disease, is defined as the presence of chronic mucosal inflammatory changes leading to ●mucosal atrophy and ●epithelial metaplasia

國重走普种大 gqing Med山eal Universi Nonspecific chronic gastritis has many etiologies that produce similar or overlapping histologic features

Nonspecific chronic gastritis has many etiologies that produce similar or overlapping histologic features

重蹇等科大学 ongging Medical University 1.Etiology and Pathogenesis arises from the types of acute inflammation. helicobacter pylori autoimmune

1.Etiology and Pathogenesis arises from the types of acute inflammation. helicobacter pylori autoimmune

重蹇等科大學 gqing Med山eal Univer 2.Classification The two main types of chronic gastritis are examples of this classification in use: O H.pylori associated chronic gastritis of the antrum with moderate activity (formerly known as Type B gastritis). ● Auto-immune associated chronic pangastritis with severe atrophy (formerly known as Type A gastritis);

2.Classification The two main types of chronic gastritis are examples of this classification in use: ● H. pylori associated chronic gastritis of the antrum with moderate activity (formerly known as Type B gastritis). ● Auto-immune associated chronic pangastritis with severe atrophy (formerly known as Type A gastritis);

重瘥普科大嚼 ongging Medical University (1)Chronic superficial Gastritis With regard to the superficial gastritis and the chronic atrophic gastritis The mucosa appears normal in thickness or even slightly expanded due to the presence of a mononuclear cell infiltrate in the superficial lamina propria.This infiltrate consists predominantly of lymphocytes and plasma cells,but eosinophils may be present as well

(1)Chronic superficial Gastritis With regard to the superficial gastritis and the chronic atrophic gastritis . The mucosa appears normal in thickness or even slightly expanded due to the presence of a mononuclear cell infiltrate in the superficial lamina propria. This infiltrate consists predominantly of lymphocytes and plasma cells, but eosinophils may be present as well．