河南农业大学：《生物化学》课程PPT教学课件（本科双语教学）第五章 脂类代谢 Lipid

Chapter 5 Lipid The mightywhales which swin in a swa ol water;and have a sea ofoil swimming in them

Chapter 5 Lipid The mighty whales which swin in a swa of water, and have a sea of oil swimming in them

The function of lipid Lipids are a class of biological molecules defined by low solubility in water and high solubility in nonpolar solvents. Function: Energy membrane

The function of lipid Lipids are a class of biological molecules defined by low solubility in water and high solubility in nonpolar solvents. Function: Energy membrane

5.1·Fatty Acids Fatty acids are either saturated (all carbon- carbon bonds are single bonds)or unsaturated (with one or more double bonds in the hydrocarbon chain).If a fatty acid has a single double bond,it is said to be saturated, and if it has more than one,ated

5.1 · Fatty Acids Fatty acids are either saturated (all carbon￾carbon bonds are single bonds) or unsaturated (with one or more double bonds in the hydrocarbon chain). If a fatty acid has a single double bond, it is said to be monounsaturated, and if it has more than one, polyunsaturated

A list of the most abundant fatty acids (M table 10.1) Common Name Systematic Name Abbreviation Structure Melting Point(C) Saturated Fatty Acids Capric n-Decanoic 10:0 CH3(CH2)COOH 31.6 Lauric n-Dodecanoic 120 CH3(CH2)1oCOOH 44.2 Myristic -Tetradecanoic 140 CH3(CH2)12COOH 53.9 Palmitic n-Hexadecanoic 160 CH3(CH2)1COOH 63.1 Stearic n-Octadecanoic 180 CH3(CH)1COOH 69.6 Arachidic n-Eicosanoic 200 CH3(CH2)1sCOOH 76.5 Behenic n-Docosanoic 220 CH(CH)COOH 81.5 Lignoceric n-Tetracosanoic 240 CH(CH)COOH 86.0 Cerotic n-Hexacosanoic 260 CHs(CH2)2COOH 88.5 Unsaturated Fatty Acids Palmitoleic cis-9-Hexadecenoic 16:lc△9 CH:(CH2)CH-CH(CH2)-COOH 0 Oleic cis-9-Octadecenoic 18:1c△9 CH(CH2)CH-CH(CH2)COOH Linoleic cs,c-9,12 18:2c△9,12 CH(CH)CH= 5 Octadecadienoic CHCH2CH=CH(CH2)COOH Linolenic al-cis9,12,15 18:3c△9,12,15 CHCH2CH-CHCH2CH= -11 Octadecatrienoic CHCH-CH-CH(CH)COOH Arachidonic al-cis5,8,1114 20:4c△5,8,11,14 CH(CH2)CH= -50 Eicosatetraenoic CHCH,CH-CHCH,CH- CHCH2CH=CH(CH)COOH Branched and Cyclic Acids CHs Tuberculostearic 1-D-10-Methyloctadecanoic CH:(CH2)CH(CH2)COOH 13.2 CH2 Lactobacillic co-(2-n-Octylcyclopropyl)- CH3(CH2);CH-CH(CH2)COOH 29 octadecanoic

A list of the most abundant fatty acids (M table 10.1)

Common Biological Fatty Acids Number of Carbons Common Name Systematic Name Symbol Structure Satrated fatty acids 12 Lauric acid Dodecanoic acid 120 CH(CH2)COOH 14 Myristic acid Tetradecanoic acid 140 CH3(CH2)COOH 16 Palmitic acid Hexadecanoic acid 160 CH:(CH2)COOH 18 Stearic acid Octadecanoic acid 180 CH3(CH2)COOH 20 Arachidic acid Eicosanoic acid 20:0 CH(CH2)COOH 2 Bchenic acid Docosanoic acid 220 CH3(CH2)2COOH 24 Lignoceric acid Tetracosanoic acid 240 CH(CH2)COOH Unsaturated fatty acids (all double bonds are cs) 16 Palmitolcic acid 9-Hexadecenoic acid 161 CH(CH)CH-=CH(CH)-COOH 18 Oleic acid 9-Octadecenoic acid 18:1 CH(CH )CH-CH(CH)-COOH 18 Linoleic acid 9.12-Octadecadienoic acid 18:2 CH:(CH2)(CH=CHCH2)2(CH2)COOH 18 a-Linolenic acid 9.12.15-Octadecatrienoic acid 18:3 CHCH(CH=CHCH)(CH2).COOH 18 y-Linolenic acid 6.9.12-Octadecatrienoic add 18:3 CH(CH2)a(CH=CHCH)(CH2)COOH 20 Arachidonic acid 5,8.11,14-Eioosatetracnoic acid 20:4 CH:(CH2)(CH=CHCH2)(CH2)2COOH 24 Nervonic acid 15-Tetracosenoic acid 2尘1 CH(CH)CH=CH(CH2)COOH

Palmitic acid Stearic acid Oleic scid Linoleie scid a-Linelenic acid Arachidonie acld

Composition of natural fats (M table 10.2) Percent Present in: Number of C Atoms Olive Beef in Chain 01 Butter" Fat Saturated 4-12 2 11 2 14 2 10 2 16 13 26 29 18 3 11 21 Unsaturated 16-18 80 40 46 Numbers do not total 100%because the substance contains small amounts of other fatty acids

Composition of natural fats (M table 10.2)

5.2 Triacylglycerol:the fat tristearin(M10.2） 0 HC-O-C-R, C-R2 0 HC-O-C-Rg 9了 WNWWWwv Triacylglycerol W

5.2 Triacylglycerol: the fat tristearin (M10.2)

HC-CH一OH H0-Ci一GH HC-CH一CH HO OHOH 0 0 0 Glycmnl 0=0 C0=0 0=C C=0C=0 Myristic Palmitoleic Stearic Tristearin aimp业tiai幼cro A mixed triacyiglycerol

Polar Bears Use Triacylglycerols to Survive Long Periods of Fasting

Polar Bears Use Triacylglycerols to Survive Long Periods of Fasting