《有机化学》课程PPT教学课件（Organic Chemistry, William A. Price, Ph.D. PPT, La Salle University, L.G.WADE, JR., 8th Edition）Carboxylic Acids Nitriles

Carboxylic Acids Nitriles Natural Products Nomenclature Acidity Preparation Reactions

Carboxylic Acids Nitriles Natural Products Nomenclature Acidity Preparation Reactions

Analgesics CO,H O OCCH? (S)+) acetyl salicylic acid ibuprofin

Analgesics ibuprofin HO2 C acetyl salicylic acid CO2 H OCCH3 O (S)(+)-

Fats and Fatty Acids CO,H palmitic acid (a fatty acid) CH2—OCR 0 CH-OCR 0 CH2-OCR R=n-C15H31 a triglyceride

Fats and Fatty Acids CO2 H palmitic acid (a fatty acid) C H2 CH CH2 OCR OCR O O O OCR a triglyceride R = n-C15H31

Prostaglandins cyclo- CO2H oxygenase HO arachadonic acid a prostaglandin OH natural mediators of inflammation

Prostaglandins a prostaglandin O HO CO2H arachadonic acid OH CO2H cyclo￾oxygenase natural mediators of inflammation

Penicillins from mold Penicillium chrysogenum PhCHCNH R CO2H R=H penicillin G R=NH2 ampicillin

Penicillins from mold Penicillium chrysogenum R= NH2 ampicillin N S CO2 H PhCHCNH O R O R = H penicillin G

From Ergot Fungus H02C、 CH3 H (+)lysergic acid NH

From Ergot Fungus (+) lysergic acid N NH HO2 C CH3 H

Common Nomenclature Prefix form HCO2H acet CH3CO2H prefix+ic+acid O propion 、C02H CO2H 6 B butyr CO2H δ-chlorovale ric acid valer CO2H

Common Nomenclature HCO2 H C H3 C O2 H CO2 H CO2 H CO2 H Prefix form acet propion butyr valer     prefix + ic + _acid CO2 H Cl -chlorovaleric acid

capro CO2H enanth CO2H capryl CO2H pelargon CO2H capr CO>H CO2H CI C Y,Y-dichloro-a-phenylcaprylic acid

CO2 H CO2 H CO2 H capro enanth capryl pelargon CO2 H CO2 H capr CO2 H Cl Cl −dichloro- -phenylcaprylic acid

I.U.P.A.C.Nomenclature drop e from alkan e and add "oic acid" OH CO2H heptanoic acid (Z)2-methyl-2-pentenoic acid CHCO2H CO2H Br cyclopentanecarboxylic acid p-bromophenylethanoic acid p-bromophenylacetic acid

I.U.P.A.C. Nomenclature O OH heptanoic acid drop e from alkan e and add "oic acid" CO2 H (Z) 2-methyl-2-pentenoic acid CO2 H cyclopentanecarboxylic acid CH2 CO2 H Br p-bromophenylethanoic acid p-bromophenylacetic acid

Dicarboxylic Acids oxalic acid HO2CCO2H or ethanedioic acid malonic acid HO2CCH2CO2H succinic acid HO2CCH2CH2CO2H 0B' glutaric acid HO2CCH2CH2CH2CO2H adipic acid HO2CCH2CH2CH2CH2CO2H a B Y pimelic acid HO2CCHCH2CH2CH2CH2CO2H

Dicarboxylic Acids HO2 CCO2 H or ethanedioic acid HO2 CCH2 C O2 H HO2 CCH2 C H2 C O2 H HO2 CCH2 C H2 C H2 C O2 H HO2 CCH2 C H2 C H2 C H2 C O2 H HO2 CCH2 C H2 C H2 C H2 C H2 C O2 H oxalic acid malonic acid succinic acid glutaric acid adipic acid pimelic acid      