精神治疗药物（PPT课件讲稿）Psychotropic drugs

Psychotropic drugs Liming Zhou(周黎明) Department of pharmacology

Psychotropic drugs Liming Zhou (周黎明) Department of pharmacology

Classification Antipsychotic Drugs Antimanic drugs Antidepressants anxiolytics

Classification ◼ Antipsychotic Drugs ◼ Antimanic drugs ◼ Antidepressants ◼ anxiolytics

Antipsychotic Drugs

Antipsychotic Drugs

Contents Overview Inreuduction of Schizophrenia Classification of antipsychotic drugs Chlorpromazine

Contents ◼ Overview ◼ Inreuduction of Schizophrenia ◼ Classification of antipsychotic drugs ◼ Chlorpromazine

Overview Antischizophrenic, neuroleptic drugs a These agents are prescribed for treating schizophrenia or management of psychotic symptoms

Overview ◼ Antischizophrenic,neuroleptic drugs ◼ These agents are prescribed for treating schizophrenia or management of psychotic symptoms

Overview a What is schizophrenia? a There appears to be a genetic component to schizophrenia There is also evidence for changes in brain structure

Overview ◼ What is schizophrenia ? ◼ There appears to be a genetic component to schizophrenia. ◼ There is also evidence for changes in brain structure

Schizophrenia size of ventricles

Schizophrenia ◼ schizophrenia ◼ Clinical Manifestations ◼ Characteristics-- perturbations affecting: ◼ language ◼ perception ◼ thinking ◼ volition ◼ Behavior ◼ social activity size of ventricles

Schizophrenia a Syndrome overview: ypically begins in late adolescence a Insidious onset Poor outcome Social withdrawal/perceptual distortions lead to chronic delusions (错觉)/ hallucinations(幻觉)

Schizophrenia ◼ Syndrome overview: ◼ Typically begins in late adolescence ◼ Insidious onset. ◼ Poor outcome. ◼ Social withdrawal /perceptual distortions lead to chronic delusions （错觉）/hallucinations （幻觉）

Schizophrenia Positive Symptoms Conceptual disorganization a Delusions hallucinations

Schizophrenia ◼ Positive Symptoms: ◼ Conceptual disorganization ◼ Delusions ◼ Hallucinations

Schizophrenia Negative Symptoms: Anhedonia(快感缺乏 Decreased emotional expression a Impaired concentration a Diminished socialization

Schizophrenia Negative Symptoms: ◼ Anhedonia (快感缺乏) ◼ Decreased emotional expression ◼ Impaired concentration ◼ Diminished socialization