上海交通大学医学院：《妇产科学》（双语） 32 Physiology of Pregnancy

Physiology of Pregnancy Liu Wei Department of ob& Gy Renji hos pital

Normal Pregnancy Pregnancy The course that, the embryo and the r fetus grow in the maternal body R Stages of pregnancy? 1. Early pregnancy: $12 weeks Mid pregnancy: 213 weeks, 527 weeks 3. Late pregnancy: 228 Weeks 4. Term pregnancy: 237 weeks, <42 weeks

Formation of Embryo atio小 1. Place; oviduct (ampulla) 2 Process capacitation→ acrosome reaction→ penetrate the zona pellucida-> second meiosis -zygote

Formation of Embryo s imolantatroe requirement"° 1) Disappear of zona pellucida 2) Formation of syncytiotrophoblast 3) Synchronized development of blastocyst and endometrium 4)Adequate progesterone

Formation of Embryo 2 Process a 1)morula(day 3 )->enter uterine cavity(day 4) early blastocyst> late blastocyst (day 6-7)>implantation 2)location- adherence- penetration

Development of embryo and fetus initio embryo:≤8 weeks 2. Fetus:29 weeks human shape

Development of embryo and fetus Circulation>° 1).fetus <>placenta- mater 2)1 umbilical vein(full of oxygen), 2 umbilical artery(lack of oxygen 3)Mixed blood (vein and artery)

Heac ss Ductus ovae InTerior Ductus enosis Umbilical venn Umbilical Piacente erter oa viscera lower trunk

Development of embryo and fetus 2, Hematology 1) Erythropoiesis s From yolk sac: 3 weeks 4 From liver: 10 weeks From bone marrow and spleen term(90%) EPO production: 32nd week

Development of embryo and fetus 2)Fetal hemoglobin Fetal hemoglobin; early pregnancy Adult hemoglobin: 32nd week Term; fetal type Hb 25%0 3)White cells Leukocytes: 8 week ymphocytes(antibody production): 123 week, thymus and spleen