《病理生理学》课程教学课件（PPT讲稿）Chapter 5 Fever

FEVERPathophysiology Department, ShiHeZi Medical College, HUST

Pathophysiology Department, ShiHeZi Medical College, HUST

Fever37℃normalSet point37℃Pyrogen affectedBTbody37℃Feverhappened

37℃ 37℃ 37℃ Set point BT normal Pyrogen affected body Fever happened Fever

Anelevationofbodytemperatureisfever?40℃36℃Physiologic elevation of body temperature

An elevation of body temperature is fever? 36 ℃ 40 ℃ Physiologic elevation of body temperature

Apathologic elevation of bodytemperature is fever?HeatstrokeHyperthyroidismCentral nervous systemdamagehyperthermia

A pathologic elevation of body temperature is fever? Heatstroke Hyperthyroidism Central nervous system damage hyperthermia

ClassificationTemperature elevationPhysiologicPathologictemperature elevationtemperature elevationHyperthermiaFever

Physiologic temperature elevation Pathologic temperature elevation Temperature elevation Hyperthermia Fever Classification

Hyperthermia is an unregulatorytemperature risingItisapassiveprocessThere is no change of the set point

Hyperthermia is an unregulatory temperature rising It is a passive process There is no change of the set point

Fever is a regulatory temperature risingItis anactiveprocessIt is the body's active reaction to pyrogenhagoNKC

Fever is a regulatory temperature rising It is an active process It is the body’s active reaction to pyrogen

How can we prove that there is no temperatureregulation dysfunction during the development of fever?HeatHighenvironmentdissipationtemperatureFeverAnimalmodelHeatlowenvironmentproductiontemperature

How can we prove that there is no temperature regulation dysfunction during the development of fever? Fever Animal model High environment temperature Heat dissipation low environment temperature Heat production

DefinitionFeveris defined as a regulatory bodytemperature elevation response to thepyrogen, it is induced by an upward shift ofthe set-point in thermoregulatorycenter

Definition Fever is defined as a regulatory body temperature elevation response to the pyrogen, it is induced by an upward shift of the set-point in thermoregulatory center

Pathogenesis

Pathogenesis