《病理生理学》课程教学课件（PPT讲稿）Chapter 1 Conspectus Of Disease

Welcome to福Q3Pathophysiology84.5市Pathophysiology departmentShiHeFiMedical College

Welcome to Pathophysiology Pathophysiology department ShiHeZi Medical College

ContentsofthelectureIntroduction2Conspectusof Disease

Contents of the lecture 1 Introduction 2 Conspectus of Disease

What is Pathophysiology?A subject to explore the rule oforigin and evolution of diseases andthe underlyingmechanisms

What is Pathophysiology? A subject to explore the rule of origin and evolution of diseases and the underlying mechanisms

Subjectsinvolved inPathophysiologyAlldiseasesseeninall clinicaldepartmentsAlldiseases reproducedin animalmodels

Subjects involved in Pathophysiology ◆ All diseases seen in all clinical departments ◆ All diseases reproduced in animal models

Differences from PhysiologyPhysiopathologyPhysiologyofDiseaseClinical PhysiologyMedicalPhysiologyPhysiology of Disordered FunctionPhysiology under diseased situation

Differences from Physiology ◆ Physiopathology ◆ Physiology of Disease ◆ Clinical Physiology ◆ Medical Physiology ◆ Physiology of Disordered Function Physiology under diseased situation

Differencesfrom Pathology"Pathology"emphasizes the structuralchangesPathophysiology deals with functionalandmetabolicalterationsandthemechanisms

Differences from Pathology ◆ “Pathology” emphasizes the structural changes ◆ Pathophysiology deals with functional and metabolic alterations and the mechanisms

The Methodologies Used inPathophysiologyAs a subject, the experiments areassigned in systemicororganiclevels.Animal studyClinicalobservationEpidemiologicalstudyFor scientificinstudiesresearch,levelsandcellularmoleculararerequired

The Methodologies Used in Pathophysiology As a subject, the experiments are assigned in systemic or organic levels. ◼ Animal study ◼ Clinical observation ◼ Epidemiological study For scientific research, studies in cellular and molecular levels are required

WhyIsPathophysiologyImportant?IAnessentialintroductiontoclinicalmedicine.Abridge:basic medicine anddiseases.Enablesustounderstandwhyandhowdiseases develop andvarious clinicalmanifestationsappear.Whataretheunderlyingmechanisms,andinso doing devise rationaltherapeutics

Why Is Pathophysiology Important? ◼ An essential introduction to clinical medicine. ◼ A bridge: basic medicine and diseases. ◼ Enables us to understand why and how diseases develop and various clinical manifestations appear. ◼ What are the underlying mechanisms, and in so doing devise rational therapeutics

HowPathophysiologyisArranged?Introduction:what pathophysiology isand whatdiseaseis.Fundamental pathological processesFluids and electrolytes imbalance,acidandbasedisturbances,stress,feveredema,ischemiaandreperfusion,shock.multiorganic dysfunction,andhypoxia

How Pathophysiology is Arranged? ◼ Introduction: what pathophysiology is and what disease is. ◼ Fundamental pathological processes: Fluids and electrolytes imbalance, acid and base disturbances, stress, fever, edema, ischemia and reperfusion, shock, multiorganic dysfunction, and hypoxia

Fundamental pathologicalprocessesSome commonandwholesetalterationsin metabolism,functionandstructure,whichmayappearin differentdisorders

Fundamental pathological processes Some common and whole set alterations in metabolism, function and structure, which may appear in different disorders