泌尿系统和生殖系统的发育（PPT讲稿）Development of Urinary system and reproductive system

Development of Urinary system and reproductive system 1. Development of kidney and ureter 2. Development of urinary bladder and urethra 3. Abnormality in urinary system 4. Development of gonad 5. Development of reproductive tracts 6. Abnormality in reproductive system

Development of Urinary system and reproductive system 1. Development of kidney and ureter 2. Development of urinary bladder and urethra 3. Abnormality in urinary system 4. Development of gonad 5. Development of reproductive tracts 6. Abnormality in reproductive system

Brd week Head segmentation Nephrotome Intermediate pronephros Mesoderm Other migration, proliferation Nephrogenic cord Mesonephros and metanephros

3rd week: Head segmentation Nephrotome → Intermediate Pronephros Mesoderm Other migration, proliferation Nephrogenic cord → Mesonephros and Metanephros

3rd week Intermediate Nephrogenic Urogenital cord ridge mesoderm Mesonephric Urinary system, ridge Genital excurrent ducts Gonadial → Gonad ridge Pudendum

Intermediate mesoderm Intermediate mesoderm ─────→ Nephrogenic cord ───→ Urogenital ridge 3rd week ─── Mesonephric ridge Gonadial ridge Urinary system, Genital excurrent ducts Gonad Pudendum

Mesonephric ridge Urogenital Gonadial ridge ridge

Urogenital ridge Gonadial ridge Mesonephric ridge

Mesonephric ridge Gonadial ridge

Gonadial ridge Mesonephric ridge

Development of urinary system Development of kidney and ureter 1. Pronephros 4th week Nephrotome (7-14th Somite) Pronephric Pronephric ubule duct Degeneration Mesonephric in 1 week duct

Nephrotome (7-14th Somite) Pronephric tubule Pronephric duct Degeneration in 1 week Mesonephric duct Development of urinary system Development of kidney and ureter 1. Pronephros 4th week

Pronephric tubule Pronephros Time: 4th week Function: no Destiny: degeneration

Pronephric tubule Pronephros Time：4th week Function：no Destiny: degeneration

Mesonephros 14-18th somite Middle part of 80 transverse s nephrogenic cord shaped tubule le Mesonephric Mesonephric bule duct Continus pronephric duct Inner end Outer end bind The end bind form renal to mesonephric to cloaca capsule du Glomerulus

Mesonephric duct Middle part of nephrogenic cord Mesonephric tubule Inner end form renal capsule Glomerulus The end bind to cloaca 80 transverse S￾shaped tubule Continus to pronephric duct Outer end bind to mesonephric duct 2. Mesonephros 14-18th somite

Time end of 4th week Function Mesonephric duct transient urinary Mesonephric tubu D estiny Most degeneration, Small part form male excurrent duct

Time ： end of 4th week Function: transient urinary Destiny: Most degeneration, Small part form male excurrent duct Mesonephric duct Mesonephric tubule

3. Metanephros o Time: begin at 5th week exist forever e Function: begin at 3th month, urinary function Position: rise gradually Metanephros

Time：begin at 5th week, exist forever Function：begin at 3th month, urinary function Position：rise gradually 3.Metanephros Metanephros