呼吸衰竭（PPT课件讲稿）Respiratory failure

Chaper 13 Respiratory failure Zhao Mingyao BMC.ZZU

Chaper 13 Zhao Mingyao BMC.ZZU

Respiration= ventilation t gas exchange Ventilation: alveoli enlarging to set up p gradient airway fluency to let gas flow gas exchange: area distance efficiency(v/Q) physiology view

Respiration = ventilation + gas exchange Ventilation: alveoli enlarging to set up P gradient airway fluency to let gas flow gas exchange: area distance efficiency (V/Q) ------ physiology view

Air Out nasal cavity aryan larynx trachea epiglottis bronchus right lung 人.了 diaphragm left lung neural

1. Concept of Repiratory Failure Respiratory system fails to adequately oxygenate the blood with/without retention of CO2, it is generally defined as a pao 60mmHg. with /without Paco2 >50mmHg

1.Concept of Repiratory Failure Respiratory system fails to adequately oxygenate the blood with/without retention of CO2 , it is generally defined as a PaO2 50mmHg

2. Classification of According to (duration Acute: minutes to days Chronic: over months to years (2)primary site Central: head injury, encephalitis Peripheral: asthma, pneumonia, emphysema

2.Classification of ~ (1)duration Acute : minutes to days Chronic: over months to years (2)primary site Central : head injury, encephalitis Peripheral: asthma, pneumonia, emphysema According to

B3)blood-gas Type I:PaO2↓ Type I:PaO2↓+PaCO2 (4 ) pathogenesis ventilation blood gas exchange: diffusion v/Q anatomy shunt

(3)blood-gas Type I : PaO2  Type II: PaO2  + PaCO2  (4)pathogenesis ventilation blood gas exchange: diffusion V/Q anatomy shunt

Section 1 Etiology and pathogenesis Respiration ventilation gas exchange

Section 1 Etiology and pathogenesis Respiration = ventilation + gas exchange

Mechanism of re 1. Hypoventilation (Restrictive Extralung intralung Central airway (2 )obstructive Pe eripheral airway

1. Hypoventilation Mechanism of RF (1)restrictive ~ (2)obstructive ~ Central airway ~ Peripheral airway ~ Extralung intralung

Ventilation(does work dynamic force overcomes resistant force (elastic nonelastic m) ----physics view

Ventilation (does work) = dynamic force overcomes resistant force (elastic ~ + nonelastic ~) ----physics view

(1) Restrictive MEDULLA CAROTID BODY Major causes: Ⅸ NERVE SPINAL CORD CNS and nerves 6 THORACIC CAGE MUSCLE Respiratory muscles chest wall AIRWAYS and pleura Lung( Alveoli) distension I Alveoli distensibility t

(1) Restrictive ~ Alveoli distensibility  Major Causes: CNS and nerves Respiratory muscles, chest wall and pleura Lung( Alveoli) distension 