北京大学：《病理学》课程PPT教学课件（英文版）Chapter Two Tissue injury Section A

Chapter Two Tissue injury Section A Cellular adaptation. Atroph Hypertrophy Hyperplasia Metaplasia

Cellular adaptation: Atrophy Hypertrophy Hyperplasia Metaplasia Chapter Two Tissue injury

CELLULARADAPTATION Excessive physiologic stresses Some pathologic stimuli. a new, but altered state preserving the viability of the cell

CELLULAR ADAPTATION • Excessive physiologic stresses. • Some pathologic stimuli. A new, but altered state preserving the viability of the cell

ATROPHY Decrease in mass of the cell HYPERTROPHY Increase in mass of the cell

ATROPHY Decrease in mass of the cell HYPERTROPHY Increase in mass of the cell

ATROPHY ● Decreased workload Loss of innervation。 Diminished blood supply. Inadequate nutrition. Loss of endocrine stimulation aging

ATROPHY • Decreased workload. • Loss of innervation. • Diminished blood supply. • Inadequate nutrition. • Loss of endocrine stimulation. • Aging

Morphology of atrophy Brown atrophy Reduction in the number of cell organelles Increase in the number of autophagic vacuoles。 Lipofuscin granules(Brown atrophy

Morphology of atrophy Brown atrophy Reduction in the number of cell organelles. Increase in the number of autophagic vacuoles. Lipofuscin granules (Brown atrophy)

正常胸腺 萎缩胸腺 ,然∵的牙

Fig 2-5

正常心脏 萎缩心脏

心肌褐色萎缩

正常心肌 萎缩心肌

心肌褐色萎缩