重庆医科大学：《重症医学》课程教学课件（讲稿，2017）Fat Embolism Syndrome

Fat Embolism Syndrome

CaseFemale,27yrs,road traffic accidentChief complaint: pain at left leg and right armArrival: awake, oriented, vital signs were stableX-ray: fracture of the femur and humerus

Case Female, 27yrs, road traffic accident Chief complaint: pain at left leg and right arm Arrival: awake, oriented, vital signs were stable X-ray: fracture of the femur and humerus

X-ray examinationFemur fractureHumerus fracture27c

X-ray examination Femur fracture Humerus fracture

Case12 hours later:tachypneatachycardiahypoxemiaconsciouslessnessIntensive care

Case 12 hours later:  tachypnea  tachycardia  hypoxemia  consciouslessness Intensive care

QuestionsWhy was this woman sent to the intensive careunit（ICU)?Why did she need respiratory support?Whathappenedtoher?

 Why was this woman sent to the intensive care unit （ICU）?  Why did she need respiratory support?  What happened to her? Questions

Fat Embolism SyndromePart IDefinitionAetiologyPathogenesisClinicalmanifestationPart IlInvestigationsDiagnosisTreatment

Fat Embolism Syndrome  Part I  Definition  Aetiology  Pathogenesis  Clinical manifestation  Part II  Investigations  Diagnosis  Treatment

Fat Embolism SyndromePartIDefinitionAetiologyPathogenesisClinicalmanifestation

Fat Embolism Syndrome  Part I Definition  Aetiology  Pathogenesis  Clinical manifestation

DefinitionFat embolism syndrome refers to theconstellation of clinical manifestations thatmay develop when fat droplets becomeimpacted in the small vessles of pulmonaryand other organs, especiallyinthebrain.Respiratoryfailure,cerebraldysfunction,petechia

Definition  Fat embolism syndrome refers to the constellation of clinical manifestations that may develop when fat droplets become impacted in the small vessles of pulmonary and other organs, especially in the brain.  Respiratory failure, cerebral dysfunction, petechia

DefinitionThe fat emboli passes into the small vessels ofthelung and otherorgans.It induces the damage, multisystem dysfunction.Petechiaovertheupperhalfof body

Definition  The fat emboli passes into the small vessels of the lung and other organs.  It induces the damage, multisystem dysfunction.  Petechia over the upper half of body

DefinitionPre-accidentCondition0FemoralveinrachunmentofEmboliResultinginCerebralion2.ArteryBrain InjurytwarctlonaEmDtoDnirErsbolusinhunos

Definition