复旦大学：《肿瘤学概论 Basics of Clinical Oncology》课程PPT教学课件（英文）肿瘤的细胞微环境和肿瘤转移 The cellular microenviroment and metastases

Fudan University Cancer Center Basic Clinical Oncology The Cellular Microenviroment and metastases Fudan University Cancer Center Prof Dr Wentao YANG L TrrE 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Basic Clinical Oncology The Cellular Microenviroment and Metastases Fudan University Cancer Center Prof. Dr. Wentao YANG

Fudan University Cancer Center Origin and History The oldest and one of the most prestigious cancer centers in China Founded in 1931 as sino Belgium radium institute by Kingdom of Belgium Formerly affiliated to Shanghai medical University(1954-2000 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Origin and History • The oldest and one of the most prestigious cancer centers in China • Founded in 1931 as Sino￾Belgium Radium Institute by Kingdom of Belgium • Formerly affiliated to Shanghai Medical University (1954-2000)

Fudan University Cancer Center 育西元影合工戚醴金院锭鐳立市海上 是R Sino-Belgium Radium Institute in 1950 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Sino-Belgium Radium Institute in 1950

Fudan University Cancer Center Today 1205-bed Cancer center 医院实最 Outpatients/year: 932,000 Inpatients/year: 40600 Operation/year: 23219 Number of employees: 1300 Affiliated to fudan University since 2000 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Today • 1205-bed Cancer Center • Outpatients/year: 932,000 • Inpatients/year: 40600 • Operation/year: 23219 • Number of employees: 1300 • Affiliated to Fudan University since 2000

Fudan University Cancer Center Basic Clinic Oncology Course Objectives: To know the etiology and biology of cancer and the situation of cancer prevention. To learn the basics of cancer diagnosis including the clinical, imaging, pathology and the labs To know the principles of cancer therapy, especially the multidisciplinary modalities for a comprehensive cancer patient care To know the frontiers of basic and clinical researches briefly 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Basic Clinic Oncology Course Objectives: • To know the etiology and biology of cancer and the situation of cancer prevention. • To learn the basics of cancer diagnosis, including the clinical, imaging, pathology and the labs • To know the principles of cancer therapy, especially the multidisciplinary modalities for a comprehensive cancer patient care • To know the frontiers of basic and clinical researches briefly

Fudan University Cancer Center Malignant versus Benign Tumors Benign(not cancer) Malignant (cancer) tumor cells grow cells invade only locally and cannot neighboring tissues, spread by invasion or enter blood vessels metastasis and metastasize to different sites Time 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center

Fudan University Cancer Center Definition of metastasis O The process whereby malignant tumors spread from their site of origin(the primary tumor)to form tumors at secondary sites(secondary tumor O Acquisition of the capability for invasion and metastasis is the hallmarks of cancer o Metastasis remains the major driver of mortality in patients with cancer. 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Definition of Metastasis ⚫ The process whereby malignant tumors spread from their site of origin (the primary tumor) to form tumors at secondary sites (secondary tumor) . ⚫ Acquisition of the capability for invasion and metastasis is the hallmarks of cancer. ⚫ Metastasis remains the major driver of mortality in patients with cancer

Fudan University Cancer Center FoV33, en Lung metastasis Bone metastasis 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Bone Metastasis Lung Metastasis

Fudan University Cancer Center E、8 Post-contrast Axial T1 Wtd MRI Post-contrast Coronal t1 Wtd MRI Brain metastasis 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Brain Metastasis

Fudan University Cancer Center F37 92525 FsE左关节 sN46n15FsE左关节 SN475 100 TH600 SEP 7 00 TF4170 M192192TR4170 TE/TE2 32/128 Fov230°230TE/E23228 FOV230230 Soft tissue sarcoma in left leg 复旦大学上海医学院肿瘤学系

复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Soft tissue sarcoma in left leg