《儿科学》课程教学资源（授课教案）23 Infantile Hepatitis Syndrome

重庆医科大学儿科学教案感染性疾病一婴儿肝炎综合征教师：许红梅授课题目TEACHINGTOPICInfantile Hepatitis Syndrome第几次课TIMES2nd教学方法METHODSClass teaching.教学对象OBJECTIVESeven years students in Grade 2007学时:TIME80minutes授课目的PURPOSEStudy Infantile Hepatitis Syndrome to know the main causes andhow to make the etiologic diagnosis本课重点EMPHASISThe main causes, clinical manifestations, labs studies, diagnosis andthe treatment本课难点DIFFICULTIESThe etiology深化与拓宽The hereditary and genetic metabolic disorders related to infantThe developmentsliver damage英语要求All in EnglishEnglish requirements践性教学安排Clinically,combined withthe patients toleam the manifestationClinical studyand treatment; To discuss the diagnosis and treatment.教材TEXTBOOKUSEDShen Xiaoming, Wang Weipin, Chief Editor,《PEDIATRICS》 7thEditone'sHahublican及参考资料REFERENCES1.胡亚美,江载芳。诸福棠实用儿科学,第 7 版.北京:人民卫生出版社,20022. Behrman RE, Kliegman RM and Jenson HB. Nelson textbook ofpediatics.16th ed.Science Press, Harcourt Asia, W.B.Saunders, 2001教具TEACHINGAIDSPPT教具PPT教学程序 Procedures详细见讲稿主要内容及安排（教学内容详细安排、教学方法的运用、师生活动设计、及时间分Details see the contents and配)arrangementThe contents and Arrangements讲稿主要内容及安排

重庆医科大学儿科学教案 感染性疾病－婴儿肝炎综合征 教师：许红梅 授课题目TEACHING TOPIC Infantile Hepatitis Syndrome 第几次课 TIMES 2nd 教学方法 METHODS Class teaching 教学对象 OBJECTIVE Seven years students in Grade 2007 学时: TIME 80 minutes 授课目的 PURPOSE Study Infantile Hepatitis Syndrome to know the main causes and how to make the etiologic diagnosis 本课重点 EMPHASIS The main causes, clinical manifestations, labs studies, diagnosis and the treatment 本课难点 DIFFICULTIES The etiology 深化与拓宽 The developments The hereditary and genetic metabolic disorders related to infant liver damage 英语要求 English requirements All in English 践性教学安排 Clinical study Clinically, combined with the patients to learn the manifestations and treatment; To discuss the diagnosis and treatment. 教材 TEXT BOOK USED Shen Xiaoming, Wang Weipin, Chief Editor，《PEDIATRICS》7th Edition，People’s Health Publication，2008 及参考资料 REFERENCES 1. 胡亚美,江载芳. 诸福棠实用儿科学.第 7 版.北京:人民卫生出版社, 2002 2. Behrman RE, Kliegman RM and Jenson HB. Nelson textbook of pediatrics.16th ed. Science Press, Harcourt Asia, W.B. Saunders, 2001 教具 TEACHING AIDS PPT 教具 PPT 教学程序 Procedures （教学内容详细安排、教学方法的运用、师生活动设计、及时间分 配） 详细见讲稿主要内容及安排 Details see the contents and arrangement The contents and Arrangements 讲稿主要内容及安排

timeneminInfantile Hepatitis SyndromePPT80[Introduction]Definition: A group of symptom complex which includes hepatocellular jaundice,pathologic physical sign of liver and abnornal liver function occurred in infancy[Etiology and PathogenesisFlowchartThecausesarecomplicatedThepathogenesisisdifferentfordfferentcausesInfnagents:iralinction(espcallyyomgaloius),BacerialinfionOther infection pathogens分2.Hereditaryand genetic metabolic disorders:1)Carbohydrate dysmetabolism2) Amino acid dysmetabolism, 3) Lipid dysmetabolism, 4) Other dysmetabolism3. Congenital Biliary malformation4. Other causes :Clinical manifestations]1.Common clinical manifestations2) jaundice : 3) hepatomegaly and/ or splenomegalyDoccurrenceininfancy4) abnormal liver function2.concomitantsymptoms1)congenitalmalformation2)nervoussystemimpairment3) ocular abnormality 4) Infection of skin, bucal mucosa, respiratory tract or digestive tract,255) nutritional disturbanceCytomegalovirus infectionEtiologySource of infectionRoute oftransmissionClinicalmanifestationcongenitalinfction2)prinatalinfction3) postnatal infection[Investigations]1. Blood routine2.Liver function test3.Etiologicexaminatior4. Imaging investigation155. Radioisotope scanning6. Screening for metabolic disease7.Biopsyof liver

means time min Infantile Hepatitis Syndrome PPT 80 [Introduction] Definition: A group of symptom complex which includes hepatocellular jaundice, pathologic physical sign of liver and abnornal liver function occurred in infancy 5 [Etiology and Pathogenesis] The causes are complicated.The pathogenesis is different for different causes. 1. Infection agents: viral infection( especially Cytomegalovirus), Bacterial infection, 3) Other infection pathogens 2.Hereditary and genetic metabolic disorders:1) Carbohydrate dysmetabolism 2) Amino acid dysmetabolism, 3) Lipid dysmetabolism, 4) Other dysmetabolism 3. Congenital Biliary malformation 4. Other causes： Flow chart 15 [Clinical manifestations] 1. Common clinical manifestations 1) occurrence in infancy： 2) jaundice：3) hepatomegaly and/ or splenomegaly 4) abnormal liver function 2. concomitant symptoms 1) congenital malformation 2) nervous system impairment 3) ocular abnormality 4) Infection of skin, bucal mucosa, respiratory tract or digestive tract, 5) nutritional disturbance Cytomegalovirus infection Etiology Source of infection Route of transmission Clinical manifestations: 1）congenital infection, 2) perinatal infection, 3) postnatal infection 25 [Investigations] 1. Blood routine 2. Liver function test 3. Etiologic examination 4. Imaging investigation 5. Radioisotope scanning 6. Screening for metabolic disease 7. Biopsy of liver 15

[Diagnosis]1.Infantile HepatitisSyndrome2.Identificationofthecauseofdisease[Treatment]1. Symptomatic and supportive treatment102. Etiological treatment3.Liver transplantation[结课]回顾课堂内容，说明重点要求掌握的内容布置见习的内容和要求ReviewQA:What are the main causes ofInfantile Hepatitis Syndrome?What are the clinical manifestations of Infantile Hepatitis Syndrome?What are the clinical manifestations ofCMV infection in infants?How to make the etiologic diagnosis for Infantile Hepatitis Syndrome?总结及补充修正授课年级总结及修正补充内容备注2006级增加图片2007级加大遗传代谢性疾病的内容

[Diagnosis] 1. Infantile Hepatitis Syndrome 2. Identification of the cause of disease 5 [Treatment] 1. Symptomatic and supportive treatment 2. Etiological treatment 3. Liver transplantation 10 [结课] 回顾课堂内容，说明重点要求掌握的内容 布置见习的内容和要求 5 Review QA： 1. What are the main causes of Infantile Hepatitis Syndrome? 2. What are the clinical manifestations of Infantile Hepatitis Syndrome? 3. What are the clinical manifestations of CMV infection in infants? 4. How to make the etiologic diagnosis for Infantile Hepatitis Syndrome? 总结及补充修正 授课年级 总结及修正补充内容 备注 2006 级 增加图片 2007 级 加大遗传代谢性疾病的内容