《儿科学》课程教学课件(PPT讲稿)23 Infantile Hepatitis Syndrome

InfantileHepatitisSyndrome
Infantile Hepatitis Syndrome

DefinitionAgroup ofsymptom complex which includeshepatocellularjaundice,pathologicphysicalsign of liver and abnornal liver functionoccurredininfancy
Defin ition □ A group of symptom complex which includes hepatocellular jaundice, pathologic physical sign of liver and abnornal liver function occurred in infancy

DefinitionAgroup ofsymptom complex which includeshepatocellular jaundice, pathologic physicalsign of liver and abnornal liver functionoccurred ininfancy
Defin ition □ A group of symptom complex which includes hepatocellular jaundice, pathologic physical sign of liver and abnornal liver function occurred in infancy

Etiology and Pathogenesis The causes arecomplicatedThepathogenesis is differentfordifferent causes
Etiology an d Pathogenesis □ The c a u s e s are complicated. □ The pathogenesis is different for different causes

1. Infection agents1)viral infection:Cytomegalovirus (CMV)Hepatitis viruses (HAV、HBV、HCV)Herps symplex virus (HSV)Rubella virusOther viruses:Varicella-Zoster virus (VZV)Epstein-Bar virus(EBV)EnterovirusHIV,etc.Pathogenesis is the virus invadedirectly or by theimmunoreactiveattack
1. Infection agents: 1) viral infection: □ Cytomegalovirus (CMV) □ Hepatitis viruses (HAV、HBV、HCV) □ Herps symplex virus (HSV) □ Rubella virus □ Other viruses: □ Varicella-Zoster virus (VZV ) □ Epstein-Bar virus (EBV) □ Enterovirus □ HIV, etc. P athogenesis is the virus invade directly or by the immunoreactive attack

2)Bacterialinfection(l)pathogenicbacteriaStaphylococcus aureus口Streptococcus口Ecoli口Salmonella口Pneumococcus口Anaerobic bacterium1Staphylococcus epidermidis, etc口(2)Pathogenesis: toxic hepatitis of sepsis(3)Clinical features:subclinical sepsis(4)Common points ofentry:oral mucosa, unbilical region,respiratorytract,urinary tract, skin, etc
2) B a c t e r i a l i n f e c t i o n ( 1 ) pathogenic bacteria □ Staphyloc occus a u reu s □ Strep tococcu s □ E coli □ Salmonella □ P n eu mococcu s □ Anaerobic bacterium □ Staphyloc occus epidermidis,etc (2) Pathogenesis: toxic hepatitis of sep sis (3) Clinical features:subclinical sep sis (4)Common points of entry: oral mucosa, unbilical region, respiratory tract, urinary tract, skin, etc

3)Otherinfectionpathogens:Toxoplasm:口Congenital ToxoplasmosisMicrospironema pallidum口Congenital syphilisFungous infection,etc
3) Other infection pathogens: □ Toxoplasm: Congenital Toxoplasmosis □ Microspironema pallidum: Congenital syphilis □ Fungous infection, etc

TORCH:TToxoplasmaOOthers R-Rubella virusCytomegalovirusHHerps symplex virus
TORCH: T—Toxoplasma O—Others R— Rubella virus C— Cytomega lovirus H—Herps symplex virus

2.Hereditary andgenetic metabolic disorders1)Carbohydratedysmetabolism Galactosemisgalactose-l-phosphate uridyltransferase deficiency deficiency Fructoseintolerancefructose bisphosphatealdolase Pompe's syndrome1)Aminoacid dysmetabolismTyrosinemia3)LipiddysmetabolismNiemann-Pick ‘sdisease, Gaucher disease or Wolman' s disease4)Otherdysmetabolism
2.Hereditary and genetic metabolic disorders 1)Carbohydrate dysmetabolism □ Galactosemis galactose-1-phosphate uridyltransferase deficiency deficiency □ Fructose intolerance fructose bisphosphate aldolase □ Pompe's syndrome 1)Amino acid dysmetabolism Tyrosinemia 3)Lipid dysmetabolism Niemann-Pick‘s disease, Gaucher disease or Wolman’s disease 4)Other dysmetabolism

Galactosemislactosegalactose +glucosegalactokinasel-galactosephosphategalactose-l-phosphate uridyltransferase1-glucosephosphateClinical features:Vomiting, difficult feeding, hypoglycemia, alack of energy,failure to thrive, cataract, jaundice, hepatomegaly , liver cirrhosis,mental retardation after several days ofmilk feedingBiochemistryexaminationblood glucosel, blood galactoset, reducing sugar test +Diagnos is : enzymatic determination
lactose □ Dia gn osis: enzymatic determination Galactosemis galactos e + glu cose galactokinase 1-galactose phosphate galactose -1-phos phate uridyltransferase 1-glucose phosphate □ Clinical features: Vomiting, difficult feeding, hypoglycemia, a lack of energy, failure to thrive, cataract, jaundice, hepatomegaly , liver cirrhosis, mental retardation after several days of milk feeding. □ Biochemistry examination: blood glucose↓, blood galactose↑, reducing sugar test +
按次数下载不扣除下载券;
注册用户24小时内重复下载只扣除一次;
顺序:VIP每日次数-->可用次数-->下载券;
- 《儿科学》课程教学课件(PPT讲稿)24 Mumps(Epidemic parotitis).pptx
- 《儿科学》课程教学课件(PPT讲稿)25 Scarlet Fever.pptx
- 《儿科学》课程教学课件(PPT讲稿)26 Rotavirus Infection in Children.pptx
- 《儿科学》课程教学课件(PPT讲稿)27 Inflammation Causes Cholesterol Redistribution by Diverting Cholesterol from Circulation to Tissue Tompartments.pptx
- 《儿科学》课程教学课件(PPT讲稿)20 Toxic Bacillary Dysentery.pptx
- 《儿科学》课程教学课件(PPT讲稿)21 Chronic Gastritis in Children.pptx
- 《儿科学》课程教学课件(PPT讲稿)06 新生儿败血症 Neonatal Septicemia.pptx
- 《儿科学》课程教学课件(PPT讲稿)07 新生儿缺氧缺血性脑病 Hypoxic-ischemic Encephalopathy(HIE).pptx
- 《儿科学》课程作业习题(试卷和答案)双语试卷A卷(答案).doc
- 《儿科学》课程作业习题(试卷和答案)双语试卷A卷(试题).doc
- 《儿科学》课程作业习题(试卷和答案)双语试卷C卷(答案).doc
- 《儿科学》课程作业习题(试卷和答案)双语试卷B卷(答案).doc
- 《儿科学》课程作业习题(试卷和答案)双语试卷B卷(试题).doc
- 《儿科学》课程作业习题(试卷和答案)双语试卷C卷(试题).doc
- 《儿科学》课程作业习题(典型病例)02 pneumonia.doc
- 《儿科学》课程作业习题(典型病例)01 ABO incompatibility of neonates.doc
- 《儿科学》课程作业习题(典型病例)03 congenital heart disease-TOF.doc
- 《儿科学》课程作业习题(典型病例)07 congenital hypothyroidism.doc
- 《儿科学》课程作业习题(典型病例)05 purulent meningitis.doc
- 《儿科学》课程作业习题(典型病例)04 iron deficiency anemia.doc
- 《儿科学》课程教学课件(PPT讲稿)22 Infantale Diarrhea and Fluid Therapy.pptx
- 《儿科学》课程教学课件(PPT讲稿)19 Pediatric Tuberculosis.pptx
- 《儿科学》课程教学课件(PPT讲稿)18 Varicella.pptx
- 《儿科学》课程教学课件(PPT讲稿)17 Measles.pptx
- 《儿科学》课程教学课件(PPT讲稿)16 Growth Hormone Deficiency.pptx
- 《儿科学》课程教学课件(PPT讲稿)15 Congenital Hypothyroidism.pptx
- 《儿科学》课程教学课件(PPT讲稿)14 Immunodeficiency.pptx
- 《儿科学》课程教学课件(PPT讲稿)13 Acute Glomerulonephritis,Nephrotic Syndrome.pptx
- 《儿科学》课程教学课件(PPT讲稿)12 Acute Convulsion in Children.pptx
- 《儿科学》课程教学课件(PPT讲稿)11 Nutritional Iron Deficiency Anemia.pptx
- 《儿科学》课程教学课件(PPT讲稿)10 Haematopoiesis and Blood Cell Counts.pptx
- 《儿科学》课程教学课件(PPT讲稿)09 Congenital Heart Disease.pptx
- 《儿科学》课程教学课件(PPT讲稿)08 Respiratory Disorders.pptx
- 《儿科学》课程教学课件(PPT讲稿)05 Neonatal Jaundice,Hemolytic Disease of Newborn.pptx
- 《儿科学》课程教学课件(PPT讲稿)04 Nutrition During Childhood.pptx
- 《儿科学》课程教学课件(PPT讲稿)03 Development.pptx
- 《儿科学》课程教学课件(PPT讲稿)02 Growth.pptx
- 《儿科学》课程教学课件(PPT讲稿)01 Introduction of Pediatrics.pptx