中国高校课件下载中心 》 教学资源 》 大学文库

《儿科学》课程教学课件(PPT讲稿)23 Infantile Hepatitis Syndrome

文档信息
资源类别:文库
文档格式:PPTX
文档页数:30
文件大小:720.64KB
团购合买:点击进入团购
内容简介
《儿科学》课程教学课件(PPT讲稿)23 Infantile Hepatitis Syndrome
刷新页面文档预览

InfantileHepatitisSyndrome

Infantile Hepatitis Syndrome

DefinitionAgroup ofsymptom complex which includeshepatocellularjaundice,pathologicphysicalsign of liver and abnornal liver functionoccurredininfancy

Defin ition □ A group of symptom complex which includes hepatocellular jaundice, pathologic physical sign of liver and abnornal liver function occurred in infancy

DefinitionAgroup ofsymptom complex which includeshepatocellular jaundice, pathologic physicalsign of liver and abnornal liver functionoccurred ininfancy

Defin ition □ A group of symptom complex which includes hepatocellular jaundice, pathologic physical sign of liver and abnornal liver function occurred in infancy

Etiology and Pathogenesis The causes arecomplicatedThepathogenesis is differentfordifferent causes

Etiology an d Pathogenesis □ The c a u s e s are complicated. □ The pathogenesis is different for different causes

1. Infection agents1)viral infection:Cytomegalovirus (CMV)Hepatitis viruses (HAV、HBV、HCV)Herps symplex virus (HSV)Rubella virusOther viruses:Varicella-Zoster virus (VZV)Epstein-Bar virus(EBV)EnterovirusHIV,etc.Pathogenesis is the virus invadedirectly or by theimmunoreactiveattack

1. Infection agents: 1) viral infection: □ Cytomegalovirus (CMV) □ Hepatitis viruses (HAV、HBV、HCV) □ Herps symplex virus (HSV) □ Rubella virus □ Other viruses: □ Varicella-Zoster virus (VZV ) □ Epstein-Bar virus (EBV) □ Enterovirus □ HIV, etc. P athogenesis is the virus invade directly or by the immunoreactive attack

2)Bacterialinfection(l)pathogenicbacteriaStaphylococcus aureus口Streptococcus口Ecoli口Salmonella口Pneumococcus口Anaerobic bacterium1Staphylococcus epidermidis, etc口(2)Pathogenesis: toxic hepatitis of sepsis(3)Clinical features:subclinical sepsis(4)Common points ofentry:oral mucosa, unbilical region,respiratorytract,urinary tract, skin, etc

2) B a c t e r i a l i n f e c t i o n ( 1 ) pathogenic bacteria □ Staphyloc occus a u reu s □ Strep tococcu s □ E coli □ Salmonella □ P n eu mococcu s □ Anaerobic bacterium □ Staphyloc occus epidermidis,etc (2) Pathogenesis: toxic hepatitis of sep sis (3) Clinical features:subclinical sep sis (4)Common points of entry: oral mucosa, unbilical region, respiratory tract, urinary tract, skin, etc

3)Otherinfectionpathogens:Toxoplasm:口Congenital ToxoplasmosisMicrospironema pallidum口Congenital syphilisFungous infection,etc

3) Other infection pathogens: □ Toxoplasm: Congenital Toxoplasmosis □ Microspironema pallidum: Congenital syphilis □ Fungous infection, etc

TORCH:TToxoplasmaOOthers R-Rubella virusCytomegalovirusHHerps symplex virus

TORCH: T—Toxoplasma O—Others R— Rubella virus C— Cytomega lovirus H—Herps symplex virus

2.Hereditary andgenetic metabolic disorders1)Carbohydratedysmetabolism Galactosemisgalactose-l-phosphate uridyltransferase deficiency deficiency Fructoseintolerancefructose bisphosphatealdolase Pompe's syndrome1)Aminoacid dysmetabolismTyrosinemia3)LipiddysmetabolismNiemann-Pick ‘sdisease, Gaucher disease or Wolman' s disease4)Otherdysmetabolism

2.Hereditary and genetic metabolic disorders 1)Carbohydrate dysmetabolism □ Galactosemis galactose-1-phosphate uridyltransferase deficiency deficiency □ Fructose intolerance fructose bisphosphate aldolase □ Pompe's syndrome 1)Amino acid dysmetabolism Tyrosinemia 3)Lipid dysmetabolism Niemann-Pick‘s disease, Gaucher disease or Wolman’s disease 4)Other dysmetabolism

Galactosemislactosegalactose +glucosegalactokinasel-galactosephosphategalactose-l-phosphate uridyltransferase1-glucosephosphateClinical features:Vomiting, difficult feeding, hypoglycemia, alack of energy,failure to thrive, cataract, jaundice, hepatomegaly , liver cirrhosis,mental retardation after several days ofmilk feedingBiochemistryexaminationblood glucosel, blood galactoset, reducing sugar test +Diagnos is : enzymatic determination

lactose □ Dia gn osis: enzymatic determination Galactosemis galactos e + glu cose galactokinase 1-galactose phosphate galactose -1-phos phate uridyltransferase 1-glucose phosphate □ Clinical features: Vomiting, difficult feeding, hypoglycemia, a lack of energy, failure to thrive, cataract, jaundice, hepatomegaly , liver cirrhosis, mental retardation after several days of milk feeding. □ Biochemistry examination: blood glucose↓, blood galactose↑, reducing sugar test +

共30页,试读已结束,阅读完整版请下载
刷新页面下载完整文档
VIP每日下载上限内不扣除下载券和下载次数;
按次数下载不扣除下载券;
注册用户24小时内重复下载只扣除一次;
顺序:VIP每日次数-->可用次数-->下载券;
相关文档