扬州大学：《组织胚胎学》课程教学课件（讲稿）软骨和骨 Cartiloge and bone

Chapter 4Cartilage & BoneHelical coursefbersvesse

Chapter 4 Cartilage & Bone

I. Cartilage1.Features of cartilage2.Structure of cartilage tissue3.Perichondrium4.Classificationof cartilage5.Growthof cartilage

Ⅰ. Cartilage 1.Features of cartilage 2.Structure of cartilage tissue 3.Perichondrium 4.Classification of cartilage 5.Growth of cartilage

1.Featuresof cartilageCartilage:organ=Cartilage tissue+perichondriumCartilage tissue is a specialized connective tissue.Cartilage tissue= Cells + matrix(fibers+ g.s.)

Cartilage: organ = Cartilage tissue + perichondrium Cartilage tissue is a specialized connective tissue. Cartilage tissue = Cells + matrix (fibers+ g.s.) 1.Features of cartilage

Avascular;Nutrients diffusion from perichondrium orsynovial fluid;No innervation;No lymphatic vessels;Chondrocytes have low metabolic activityFunction: support, connection, slidingsurfaceforjoints

Avascular; Nutrients diffusion from perichondrium or synovial fluid; No innervation; No lymphatic vessels; Chondrocytes have low metabolic activity. Function: support, connection, sliding surface for joints

2. Structure of cartilagetissueCellsChondrocytes: located within matrix (lacunae)Extracellularmatrix(cartilagematrix):[Fibers : Collagen and elastic fibersGround substance:hyaluronicacid,proteoglycans,glycoproteins

2. Structure of cartilage tissue Cells Chondrocytes: located within matrix (lacunae) Extracellular matrix (cartilage matrix): Fibers : Collagen and elastic fibers Ground substance: hyaluronic acid, proteoglycans, glycoproteins

1)chondrocyte:LM:embedded in cartilagelacunaeperipheral cells:--smallandimmature--singleandflattenedcentral cell:--large and mature,--round and in group of2-8 cells--smallandroundnucleus--basophiliccytoplasm2

1)Chondrocyte: LM: • embedded in cartilage lacunae • peripheral cells: -small and immature -single and flattened • central cell: -large and mature, -round and in group of 2-8 cells -small and round nucleus -basophilic cytoplasm

Cartilage lacunae: matrix cavityCartilage capsule: on the surface of the lacunae;strong basophilic (more CMP,more acidicsulphate)cap

Cartilage lacunae: matrix cavity Cartilage capsule: on the surface of the lacunae; strong basophilic (more CMP, more acidic sulphate) cap

*isogenousgroup: several cells locates inone lacuna, which are derived from asingle(same)parent cell

*isogenous group: several cells locates in one lacuna, which are derived from a single(same) parent cell

EM:rich in RER, free ribosome and Golgi complexFunction:producingcartilagematrix

EM: rich in RER, free ribosome and Golgi complex. Function: producing cartilage matrix

CM-