《微生物学 Microbiology》课程PPT教学课件（英文版）microbial diseases of the skin and eyes 1/2

Chapter 21,part A Microbial Diseases of the Skin and Eyes

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings B.E Pruitt & Jane J. Stein Chapter 21, part A Microbial Diseases of the Skin and Eyes

Skin Hair shaft Salt inhibits microbes Sweat pore Stratum corneum 。Lysozyme hydrolyzes Hair erector Epidermis muscle peptidoglycan 。Fatty acids inhibit Blood vessels Hair follicle some pathogens Dermis Nerve 88t8and perspiration) Figure 21.1

Skin • Salt inhibits microbes • Lysozyme hydrolyzes peptidoglycan • Fatty acids inhibit some pathogens Figure 21.1

Mucous Membranes ·Line body cavities Epithelial cells attached to an extracellular matrix 。Cells secrete mucus 。Some have cilia

• Line body cavities • Epithelial cells attached to an extracellular matrix • Cells secrete mucus • Some have cilia Mucous Membranes

Normal Microbiota of the Skin Gram-positive,salt- tolerant bacteria ·Staphylococci 。Micrococci ·Diphtheroids (a Figure 14.1a

• Gram-positive, salt￾tolerant bacteria • Staphylococci • Micrococci • Diphtheroids Normal Microbiota of the Skin Figure 14.1a

Microbial Diseases of the Skin 。Exanthem Skin rash arising from another focus of infection 。Enanthem Mucous membrane rash arising from another focus of infection

• Exanthem • Skin rash arising from another focus of infection • Enanthem • Mucous membrane rash arising from another focus of infection Microbial Diseases of the Skin

Microbial Diseases of the Skin 1 cm 1 cm Fluid Fluid (a)Vesicle (b)Bulla i 1cm 1 cm Pus (c)Macule (d)Pustule(papule) Figure 21.2

Microbial Diseases of the Skin Figure 21.2

Staphylococcal Skin Infections 。S.epidermidis Gram-positive cocci,coagulase-negative Staphylococcus aureus Gram-positive cocci,coagulase-positive 。Leukocidin 。Exfoliative toxin

• S. epidermidis • Gram-positive cocci, coagulase-negative • Staphylococcus aureus • Gram-positive cocci, coagulase-positive • Leukocidin • Exfoliative toxin Staphylococcal Skin Infections

Staphylococcal Skin Infections (b) Figure 21.3

Staphylococcal Skin Infections Figure 21.3

Staphylococcal Skin Infections 。Folliculitis Infections of hair follicles 。sty Folliculitis of an eyelash 。Furuncle Abscess;pus surrounded by inflamed tissue 。Carbuncle Inflammation of tissue under the skin

Staphylococcal Skin Infections • Folliculitis • Infections of hair follicles • Sty • Folliculitis of an eyelash • Furuncle • Abscess; pus surrounded by inflamed tissue • Carbuncle • Inflammation of tissue under the skin

Staphylococcal Skin Infections Impetigo of the newborn 。Toxemia Scalded skin syndrome 。Toxic shock syndrome Figure 21.4

Staphylococcal Skin Infections • Impetigo of the newborn • Toxemia • Scalded skin syndrome • Toxic shock syndrome Figure 21.4