《微生物学 Microbiology》课程PPT教学课件（英文版）microbial diseases of urinary and reproductive system

Chapter 26 Microbial Diseases of the Urinary and Reproductive Systems

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings B.E Pruitt & Jane J. Stein Chapter 26 Microbial Diseases of the Urinary and Reproductive Systems

Microbial Diseases of the Urinary and Reproductive Systems Microbes usually enter the urinary system through the urethra Microbes usually enter the reproductive system through the: Vagina (females)or urethra(males)

Microbial Diseases of the Urinary and Reproductive Systems • Microbes usually enter the urinary system through the urethra • Microbes usually enter the reproductive system through the: • Vagina (females) or urethra (males)

Female Urinary Organs Inferior- Aorta vena cava Kidneys Ureters Urinary bladder Urethra Figure 26.1

Female Urinary Organs Figure 26.1

Female Reproductive Organs Uterine (fallopian) tube Fimbriae Ovary Uterus Rectum Pubic bone Cervix Urinary bladder Vagina Urethra Clitoris Anus Labium Labium minus majus (a)Side view section of female pelvis showing reproductive organs. Figure 26.2a

Female Reproductive Organs Figure 26.2a

Male Reproductive Urinary Organs Ureter Rectum Urinary bladder Seminal vesicle Pubic bone Ductus (vas) Ejaculatory duct deferens Prostate gland Urethra- Anus Penis Epididymis Urethral Testis opening Scrotum- Side view section of male pelvis. Figure 26.3

Male Reproductive & Urinary Organs Figure 26.3

Normal Microbiota Urinary bladder and upper urinary tract sterile Lactobacilli predominant in the vagina >1,000 bacteria/ml or 100 coliforms/ml of urine indicates infection

• Urinary bladder and upper urinary tract sterile • Lactobacilli predominant in the vagina • >1,000 bacteria/ml or 100 coliforms/ml of urine indicates infection Normal Microbiota

Cystitis ·Usually caused by 。E.coli ·S.saprophyticus 。May also be caused by ·Proteus 。Klebsiella ·Enterococcus ·Pseudomonas E.coli usually causes pyelonephritis Antibiotic-sensitivity tests may be required before treatment

• Usually caused by • E. coli • S. saprophyticus • May also be caused by • Proteus • Klebsiella • Enterococcus • Pseudomonas • E. coli usually causes pyelonephritis • Antibiotic-sensitivity tests may be required before treatment Cystitis

Leptospirosis Leptospira interrogans ·Reservoir:Dogs and rats 。Transmitted by skin/mucosal contact from urine- contaminated water 。 Diagnosis:Isolating bacteria or serological tests Figure 26.4

Leptospirosis Figure 26.4 • Leptospira interrogans • Reservoir: Dogs and rats • Transmitted by skin/mucosal contact from urine￾contaminated water • Diagnosis: Isolating bacteria or serological tests

Sexually Transmitted Diseases (STDs ·Prevented by condoms Treated with antibiotics

• Prevented by condoms • Treated with antibiotics Sexually Transmitted Diseases (STDs )

Gonorrhea 500 450 400 350 300 250 200 150 100 50 0 1942194719521957196219671972197719821987199219972002 Year (a)Incidence of gonorrhea in the United States from 1942 to 2002 Figure 26.5a

Gonorrhea Figure 26.5a