《生物化学》课程教学资源（PPT课件）18 维生素 Vitamins

Vitamins

Vitamins

overviewVitamins are organiccompoundsrequiredbythebodyintraceamounts performspecificcellularfunctions.Vitamins cannot besynthesizedbyhuman,andthereforemustbe suppliedby thediet

overview Vitamins are organic compounds required by the body in trace amounts perform specific cellular functions. Vitamins cannot be synthesized by human , and therefore must be supplied by the diet

overviewVitaminsFat-soluble: Vitamin A,D,E,K

overview Vitamins Water soluble: B￾complex and Vitamin C Fat-soluble: Vitamin A, D, E, K

Vitamin supplementsTraditionalrole of vitaminsupplements:In the past, supplementationofthe diet with vitamins wasreserved forpatientsat riskfornutritionaldeficiencies

Vitamin supplements Traditional role of vitamin supplements: In the past, supplementation of the diet with vitamins was reserved for patients at risk for nutritional deficiencies

.Vitamin supplementsVitaminsupplementationinthegeneral population:Vitaminsupplementationisslowly but inexorably makingatransition from being a fadregimento becoming respectabletherapy

Vitamin supplements Vitamin supplementation in the general population: Vitamin supplementation is slowly but inexorably making a transition from being a fad regimen to becoming respectable therapy

Water-soluble vitaminsThiamine(vitaminB1):Thiaminepyrophosphate(TPP)serves as a coenzyme in theoxidative decarboxylationof a-keto acids, and in the formationor degradation of a-ketols bytransketolase

Water-soluble vitamins Thiamine(vitamin B1): Thiamine pyrophosphate(TPP) serves as a coenzyme in the oxidative decarboxylation of α– keto acids, and in the formation or degradation of α–ketols by transketolase

Water-soluble vitamins1:Riboflavin(vitaminB2):Thetwo biologically activeformsareflavinmononucleotideandflavin adeninedinucleotideWhichareeachcapableofreversiblyacceptingtwohydrogenatoms,formingFMNH2OrFADH2

Water-soluble vitamins Riboflavin(vitamin B2): The two biologically active forms are flavin mononucleotide and flavin adenine dinucleotide. Which are each capable of reversibly accepting two hydrogen atoms, forming FMNH2 or FADH2

Water-soluble vitaminsNiacin(vitaminpp):The biologically active coenzymeforms arenicotinamideadeninedinucleotide and nicotinamideadenine dinucleotidephosphatewhichserveascoenzymesinoxidation-reductionreactions

Water-soluble vitamins Niacin(vitamin pp): The biologically active coenzyme forms are nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, which serve as coenzymes in oxidation-reduction reactions

Water-soluble vitaminsBiotin:Biotinisa coenzymeincarboxylationreactions,in whichitserves asa carrier ofactivatedcarbondioxide

Water-soluble vitamins Biotin: Biotin is a coenzyme in carboxylation reactions, in which it serves as a carrier of activated carbon dioxide

Water-soluble vitaminsPantothenicacid:Pantothenic acidis a componentof coenzymeA,whichfunctionsinthetransfer of acylgroups

Water-soluble vitamins Pantothenic acid: Pantothenic acid is a component of coenzyme A, which functions in the transfer of acyl groups