天津大学理学院：《高等有机化学》（英文版）PPT课件 Introduction and basic reactions（余志芳）

Organic Synthesis Bai. Zheng wu

Organic Synthesis Bai, Zheng Wu

Part I Introduction 1. The development history of organic synthesis 2. The influences of organic synthesis on organic chemistry 3. The research scope of organic synthesis

Part I Introduction 1. The development history of organic synthesis 2. The influences of organic synthesis on organic chemistry 3. The research scope of organic synthesis

Partl Introduction a Find new reactions b Synthesize new compounds with special functions C. Research on natural products

a. Find new reactions b. Synthesize new compounds with special functions c. Research on natural products Part I Introduction

4. Development trends of organic synthesis a Chiral synthesis (stereo-chemistry in reactions) b. Bio-catalytically organic synthesis C. Utilization of special methods in organic synthesis

4. Development trends of organic synthesis a. Chiral synthesis (stereo-chemistry in reactions) b. Bio-catalytically organic synthesis c. Utilization of special methods in organic synthesis

Part l Basic reactions

Part II Basic reactions

Oxidation reaction 1. Oxidation of side chain of aromatic compounds CH3 COOH KMno H

Oxidation reaction 1. Oxidation of side chain of aromatic compounds CH3 COOH KMnO4 H +

CH H3C—C—CH3 KMnO H Frequently used oxidants KMnO4, K2 Cr2O, O3/Zn, O3 O. Ch3COOOH

Frequently used oxidants: C CH3 CH3 H3 C KMnO4 H + KMnO4, K2 Cr 2 O7, O3/Zn, O3, O2, CH3 COOOH

2. Oxidation of aromatic compounds 02 V205

2. Oxidation of aromatic compounds O2 V2O5 O O O

Reduction reaction 1. Hydrogenation(氢化)

Reduction reaction 1. Hydrogenation (氢化)

3. Oxidation of olefins C-C O C=0+O-C O C O C HO oH OI C

3. Oxidation of olefins C C [O] C O + O C C C [O] C C O C C [O] C C HO OH