中国人民解放军陆军军医大学（第三军医大学）：研究生《生命科学综合》核心课程PPT教学课件_10 细胞重要生命活动及其研究（1/2，王韵）

三民驾种 COLLEGE OF MEDICINE THIRD MIILITARY MEDICAL UNIVERSITY 细胞重要生命活动及其研究 细胞生物学教研室 王韵 Tel:68752252

细胞生物学教研室 王韵 Tel: 68752252 THIRD MIILITARY MEDICAL UNIVERSITY COLLEGE OF MEDICINE THIRD MIILITARY MEDICAL UNIVERSITY COLLEGE OF MEDICINE 细胞重要生命活动及其研究

1.The charactaristics of life and cells are the basic unit of life A. Living things are made of cells or cell products SEA Chemco dark cloud of hot mineral-rich water anaerobic lithotrophic hydrothermal vent invertebrate animal community chimney made from precipitated metal sulfides 2-3°c sea floor 350°c percolation hot mineral solution hot basalt

1.The charactaristics of life and cells are the basic unit of life A. Living things are made of cells or cell products

B. Living things use energy and responds to their environment. All metabolic activity is based on cells.

B. Living things use energy and responds to their environment. All metabolic activity is based on cells

C Living things reproduce. The cell is the foundation f reproduce and the bridge of inheritance

C. Living things reproduce. The cell is the foundation of reproduce and the bridge of inheritance

D. Living things grow. The cell is the growing and developing basis of life 6 cm longl 30 cm in length eks (b)14 weeks (e)20 weeks Human fetal development

D. Living things grow. The cell is the growing and developing basis of life Human fetal development

Cell (nucleus) is totipotent, which can create a new organism of the same type 取出A 细胞,体外培养 使之 处于静息期 取出B羊的卵细胞 并除去细胞核 培养皿中取出 其中一个细胞的 细胞核 将乳腺细胞的核 注入去核的卵细胞中重组卵细胞体外培养 植入C羊的子宫内“多莉”羊 B

Cell (nucleus) is totipotent, which can create a new organism of the same type

F Living things adapt to their environment Fish Salamander Turtle chicken Rabbit Human 893 ti 88

E. Living things adapt to their environment

Overview of the birth. lineage, and death of cells Cell growth Symmetric division Cell birth Cell growth Asymmetric Cell division death Cell lineage

Overview of the birth, lineage, and death of cells

2. Regulation of cell activity A. Control of cell growth and cell division EXTRACELLULAR FACTOR GROWTH FACTORMITOGEN CELL GROWTH CELL DIVISION CELL GROWTH CELL DIVISION EXTRACELLULAR FACTOR CELL GROWTH CELL DIVISION

2.Regulation of cell activity A. Control of cell growth and cell division

B. Signal pathway in cell life regulation growth factor growth factor receptor PI3-kinase protein kinase activation actIV active eIF4E phosphorylated S6 kinase increased mRNA translation ↓ STIMULATION OF CELL GROWTH Growth factors promote cell growth

B. Signal pathway in cell life regulation Growth factors promote cell growth