复旦大学：《皮肤病学 Dermatology》课程教学资源（PPT课件）玫瑰糠疹相关皮肤疾病 Pityriasis rosea

Pityriasis rosea Lianjun Chen Huashan Hospital

Pityriasis rosea Lianjun Chen Huashan Hospital

Definition an acute, self-limited skin disease characterized by the presence of rosy-coloured >round to oval macular lesions with a rim of fine scales appear most common in crops on the trunks and proximal extremities

• an acute, self-limited skin disease • characterized by the presence of ➢ rosy-coloured ➢round to oval macular lesions ➢ with a rim of fine scales • appear most common in crops on the trunks and proximal extremities. Definition

Epidemiology Most cases of pityriasis rosea occur in young healthy persons, the majority of whom are between the ages of 10 and 35 years Its peak incidence is during adolescence, and it is rarely diagnosed before the age of 2 years. There is no racial predilection and it is found worldwide There is a slight female predominance, and some studies have even suggested a female: male ratio of 2: 1. The typical eruption lasts 6 to 8 weeks, though exceptionally it can persist for 5 months or longer Some authors report a modest seasonal variation with peaks in the spring and fall

Epidemiology Most cases of pityriasis rosea occur in young healthy persons, the majority of whom are between the ages of 10 and 35 years. Its peak incidence is during adolescence, and it is rarely diagnosed before the age of 2 years. There is no racial predilection and it is found worldwide. There is a slight female predominance, and some studies have even suggested a female : male ratio of 2 : 1. The typical eruption lasts 6 to 8 weeks, though exceptionally it can persist for 5 months or longer. Some authors report a modest seasonal variation with peaks in the spring and fall

Etiology and pathogenesis The etiology is unknown A viral etiology is frequently proposed. There is some evidence implicating hhvo &7 infection in the pathogenesis

The etiology is unknown. A viral etiology is frequently proposed. There is some evidence implicating HHV6 &7 infection in the pathogenesis . Etiology and Pathogenesis

Clinical manifestation Predominantly seen in adolescents and young adults during spring and fall Occur mostly on the trunks and proximal extremities Lasting for about 6-8 weeks or longer Self-limited Recurrences are regarded as unusual

➢ Predominantly seen in adolescents and young adults during spring and fall. ➢ Occur mostly on the trunks and proximal extremities. ➢ Lasting for about 6-8 weeks or longer. ➢ Self-limited. Recurrences are regarded as unusual. Clinical Manifestation

Clinical manifestation The initial lesion is frequently a single, 2-5cm or bigger round plaque, names as"Herald patch Within several days, smaller oval maculans appear, with a wrinkled, salmon-colored central area and a darker red peripheral zone with gyrate border separated by a collarette of fine scaling. The lesions distribute with their long axis following Langer's lines of cleavage

Clinical Manifestation ➢ The initial lesion is frequently a single, 2-5cm or bigger round plaque,names as “Herald patch”. ➢ Within several days, smaller oval maculars appear, with a wrinkled, salmon-colored central area and a darker red peripheral zone with gyrate border ,separated by a collarette of fine scaling . The lesions distribute with their long axis following Langer's lines of cleavage

Herald patch

Herald patch

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