复旦大学：《皮肤病学 Dermatology》课程教学资源（PPT课件）皮肤组织结构与解剖学 Structure and Function of Human Skin（英文）

Structure and function of human skin Lianjun chen Huashan Hospital

Structure and Function of Human Skin Lianjun Chen Huashan Hospital

Importance of the study of skin diseases Common and prevalent diseases Skin beauty and health care D reflection of the body health paraneoplastic skin diseases Sex Transmitted Disease(STD), AIDS, other contagious diseases

Importance of the study of skin diseases Common and prevalent diseases Skin beauty and health care reflection of the body health （paraneoplastic skin diseases) Sex Transmitted Disease(STD), AIDS, other contagious diseases

OUTLINE Introduction of the skin Microstructure of the skin E epidermis The basement membrane zone Dermis Subcutis Appendageal Structure The function of the skin

OUTLINE Introduction of the Skin Microstructure of the skin – Epidermis – The basement membrane zone – Dermis – Subcutis – Appendageal Structure The function of the skin

Introduction The single biggest organ in the body Cover an average area of 1.5 m Varying thickness(0.4-4mm) Different color by the race age, gender location Perform many vital roles

Introduction The single biggest organ in the body Cover an average area of 1.5 m2 Varying thickness (0.4-4mm) Different color by the race, age, gender & location Perform many vital roles

Microstructure of the skin epidermis Dermis Subcutis a The basement membrane zone Appendageal Structure

Microstructure of the skin Epidermis Dermis Subcutis The basement membrane zone Appendageal Structure

The skin Free nerve endings Hair Merkel's Meissner's Sebaceous disc corpuscle gland Epiderm Basement membrane zone Arrector pili muscle Dermis Rutfini's Pacinian corpuscle corpuscle Sweat gland Subcutaneous Connective fa fibrous tissue Muscle Nerve in Arte

Epidermis Derived from ectoderm The celluar external layer Keratinocyte 角质层 1透明层 non-keratinocyte J颗粒层 Melanocyte 格 棘细胞层 Langerhans cell Merkel cell O 基底层 黑素细胞

Epidermis Derived from ectoderm The celluar external layer – Keratinocyte – non-keratinocyte Melanocyte Langerhans’ cell Merkel cell

Keratinocytes stratum basale, basal cell layer stratum spinosum, prickle cell layer stratum granulosum, granular layer stratum lucidum stratum corneum, horny layer

Keratinocytes stratum basale, basal cell layer stratum spinosum, prickle cell layer stratum granulosum, granular layer stratum lucidum stratum corneum, horny layer

Stratum corneum Stratum granulosum Stratum o spinosum 1 Stratum basale Langerhans' Basement Melanocyte cell membrane Keratinocyte Rete ridge