扬州大学：《妇产科学》课程教学课件（PPT讲稿）36 卵巢癌 OVARIAN CANCER

OVARIAN CANCER

OVARIAN CANCER

OVARIANTUMOURSDefinitionOvarian tumors may arise at any age,but are commonest between 30 and 60.1.Ovarian tumors are particularly liable to beor to become malignant2.Intheir early stagestheyareasymptomatic and painless.3.They may grow to a large size and tend toundergo mechanical complications such astorsion and perforation.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 2 Definition Ovarian tumors may arise at any age, but are commonest between 30 and 60. 1.Ovarian tumors are particularly liable to be or to become malignant. 2.In their early stages they are asymptomatic and painless. 3.They may grow to a large size and tend to undergo mechanical complications such as torsion and perforation. OVARIAN TUMOURS

CARCINOMAOFTHEOVARYDefinitionIn developed countries, women have alifetime risk of developing ovarian cancerof about 1.4%, which is slightly greaterthan the risk of cervical or endometrialcancers, but well below the 7% averagerisk of breast cancer.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 3 Definition In developed countries，women have a lifetime risk of developing ovarian cancer of about 1.4%，which is slightly greater than the risk of cervical or endometrial cancers, but well below the 7% average risk of breast cancer． CARCINOMA OF THE OVARY

CARCINOMAOFTHE OVARYRiskFactorGenetic factor are sometimes involvedas in the Lynch Syndrome of familialbreast colorectal and ovariancancer. Ovulation induction withClomiphene over more than year carries aO-fold increased risk of ovarian cancerLong-term ora1 contraceptive use reducesthe incidence of ovarian cancers.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 4 Risk Factor Genetic factor are sometimes involved、 as in the Lynch Syndrome of familial breast colorectal and ovarian cancer．Ovulation induction with Clomiphene over more than year carries a l0-fold increased risk of ovarian cancer, Long-term ora1 contraceptive use reduces the incidence of ovarian cancers． CARCINOMA OF THE OVARY

CARCINOMA OFTHE OVARYIncidenceNearly 25% of all ovarian neoplasmare malignant. Approximately 80%of them are primary growths of theovary、 the remainder beingsecondary, usually carcinomata.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 5 Incidence Nearly 25% of all ovarian neoplasm are malignant．Approximately 80％ of them are primary growths of the ovary、the remainder being secondary，usually carcinomata． CARCINOMA OF THE OVARY

CARCINOMA OF THEOVARYPrimary Carcinoma of the Ovary80% of all cases of primarycarcinoma of the ovary arise in serousormucinous cysts.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 6 Primary Carcinoma of the Ovary 80％ of all cases of primary carcinoma of the ovary arise in serous or mucinous cysts. CARCINOMA OF THE OVARY

CARCINOMA OFTHE OVARYSolid Carcinoma of the OvaryThis accounts for 10% of primarycarcinoma. It is arise commonly bilateralbut one tumor is usually larger than theother. The ovarian shape is retained for atime and there is a well-marked pedicle butsoon the tumors become fixed. Secondarydeposits occur in the omentum and ascitesdevelops.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 7 Solid Carcinoma of the Ovary This accounts for 10% of primary carcinoma. It is arise commonly bilateral but one tumor is usually larger than the other. The ovarian shape is retained for a time and there is a well-marked pedicle but soon the tumors become fixed. Secondary deposits occur in the omentum and ascites develops. CARCINOMA OF THE OVARY

CLINICALFEATURESOFOVARIANTUMOURSSymptoms due to SizeLackofspecificanyovariantumorssymptoms,are often large by the timethe doctor is consulted.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 8 Symptoms due to Size Lack of any specific symptoms, ovarian tumors are often large by the time the doctor is consulted. CLINICAL FEATURES OF OVARIAN TUMOURS

functionMenstrualisseldom upset, and any irregularityisattributed to the patient's ‘time oflife'.2003-10-27OvarianCancer

2003-10-27 Ovarian Cancer 9 Menstrual function is seldom upset, and any irregularity is attributed to the patient’s ‘time of life’

She maythather/ have noticedtightclothesantgettingareattributed this to weight gain or, ifthe abdominal swelling has coincidedwith amenorrhea she may believeherself to be pregnant.102003-10-27Ovarian Cancer

2003-10-27 Ovarian Cancer 10 She may have noticed that her clothes are getting tight ant attributed this to weight gain or, if the abdominal swelling has coincided with amenorrhea she may believe herself to be pregnant