武汉大学生命科学学院：《分子生物学》（英文版）Welcome to My Molecular Biology Lecture

Welcome to My Molecular Biology Lecture @博来字 Wuhan University

Welcome to My Molecular Biology Lecture

Molecular Biology of the Gene, 5/E ---Watson et al. ( 2004) Part l: Chemistry and Genetics Part l: Maintenance of the Genome Part l: Expression of the Genome Part IV: Regulation Part v: Methods Wuhan universit

Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods

Part ll: Maintenance of the genome dedicated to the structure of DNA and the processes that opagate传递), maintain《保主 and alter(改变】 it from one cel generation to the next

Part II: Maintenance of the Genome Dedicated to the structure of DNA and the processes that propagate (传递), maintain (保持) and alter (改变) it from one cell generation to the next

Maintenance of the Genome Ch 6: The structures of dna and rna Ch7: Chromosomes. chromatins and the nucleosome Ch 8: The replication of DNA Ch 9: The mutability and repair of DNA PROPAGATE AINTAIN Ch 10: Homologous recombination at the molecular level Ch 11: Site-specific recombination and transposition of DNA ALTER

Maintenance of the Genome Ch 6: The structures of DNA and RNA Ch 7: Chromosomes, chromatins and the nucleosome Ch 8: The replication of DNA Ch 9: The mutability and repair of DNA Ch 10: Homologous recombination at the molecular level Ch 11: Site-specific recombination and transposition of DNA PROPAGATE & MAINTAIN ALTER

CHAPTER 6 The structures of dNA and rNa How do the structures of dna and rna account for their functions?

CHAPTER 6 The Structures of DNA and RNA How do the structures of DNA and RNA account for their functions?

OUTLINE 1 DNA Structure 2.DNA Topology 3.RNA Structure

OUTLINE 1.DNA Structure 2.DNA Topology 3.RNA Structure

DNA STRUCTURE 1. The building blocks and base pairing 2. The structure: two polynucleotide chains are twisting around each other in the form of a double helix

DNA STRUCTURE 1. The building blocks and base pairing. 2. The structure: two polynucleotide chains are twisting around each other in the form of a double helix

DNA building blocks sssm Base(碱基) Nucleoside(核苷) Nucleotide(核苷酸) is the fundamental building block of DNA

DNA STRUCTURE ( ) 1 DNA building blocks Base (碱基) Nucleoside (核苷) Nucleotide (核苷酸) is the fundamental building block of DNA

adenine NH Bases in dNa H一 Adenine(A) guanine Purines N9 Guanine(G) N N cytosine H yrimidine Cytosine(C) H N pyrimidines thymine Thymine(T) N 004 Pearson Education, Inc, publishing as benjar

Purines pyrimidines Adenine (A) Guanine (G) Cytosine (C) Thymine (T) N9 N1 Bases in DNA

Each bases has its preferred tautomeric form (Related to Ch 9) amino ImIno N keto enol N H一 H N H H-bond donor H-bond acceptor Copyright o 2004 Pearson Education, Inc. publishing as Benjamin Cummings

Each bases has its preferred tautomeric form (Related to Ch 9)