中国医科大学：《妇产科学》课程教学资源（PPT课件讲稿，英文版）Amniotic Fluid Embolism

Amniotic Fluid embolism Page 251

Amniotic Fluid Embolism Page 251

You should rember It is axiomatic that when a choice must be made. maternal considerations take perference over those of the fetus

You should rember! • It is axiomatic that when a choice must be made, maternal considerations take perference over those of the fetus

Prognosis Perinatal outcomes are dismal with amniotic fluid embolism. Few conditions in medicine have potential for such sudden devastation We are aware of one case during labor in which mother and baby not only died, but the visiting grandmother also suffered a fatal myocardial infarction during resuscitation efforts on her daughter!

Prognosis • Perinatal outcomes are dismal with amniotic fluid embolism. Few conditions in medicine have potential for such sudden devastation. We are aware of one case during labor in which mother and baby not only died, but the visiting grandmother also suffered a fatal myocardial infarction during resuscitation efforts on her daughter!

Defition Amniotic Fluid Embolism is a complex condition characterized by the abrupt onset of pulmonary embolism, shock and DIC Incidence varies greatly

Defition • Amniotic Fluid Embolism is a complex condition characterized by the abrupt onset of pulmonary embolism, shock and DIC. • Incidence varies greatly

Etiology Pressure increasing uterinehypertonus, tetanic, oxytocin open vessles. traumatic, laceration membrane changing fetal death, dystocia

Etiology • Pressure increasing: • uterinehypertonus,tetanic,oxytocin • open vessles:traumatic, laceration • membrane changing:fetal death,dystocia

pathophysiology Emblus(amniotic fluid component+fibrin) allergic reaction mechanic block +vagus nerve(spasm)----blood return decreasing---peripheral circulation faiture lypertetion of pulmonary artery---pulmonary edema---left heart falure+respiratory failure -coagulopathy---Dl general ischemia-enal failure

pathophysiology • Emblus(amniotic fluid component+fibrin)----- allergic reaction • --mechanic block+vagus nerve(spasm)----blood return decreasing---peripheral circulation faiture • --hypertetion of pulmonary artery---pulmonary edema---left heart faiure+respiratory failure • --coagulopathy---DIC • --general ischemia—renal failure

Clinical manifestation A time of onset B circulation and respiratory failure C shock, DIC----bleeding D. renal failure

Clinical manifestation • A. time of onset • B. circulation and respiratory failure • C. shock, DIC----bleeding • D. renal failure

di agnosis Emergent: typical clinical manifestation Pulmonary edema Definitive diagnosis: aspiration debris +DIC autopsy

diagnosis • Emergent : typical clinical manifestation • Pulmonary edema • Definitive diagnosis: aspiration:debris +DIC • autopsy

treatment 1. correct r&c failure 2.correct coagulopathy, DIC, renal dysfunction 3. Anti-allergic reaction 4. obstetric management

treatment • 1.correct R&C failure • 2.correct coagulopathy, DIC, renal dysfunction • 3.Anti-allergic reaction • 4.obstetric management

Chapter 20 genetic counseling, genetic screening, prenatal diagnosispage202

Chapter 20 genetic counseling, genetic screening, prenatal diagnosispage202