中国医科大学：《妇产科学》课程教学资源（PPT课件讲稿，英文版）Cervical tumor

Cervical tumor

Cervical tumor

Cervical intraepithelial neoplasia(CiN)

Cervical intraepithelial neoplasia(CIN)

Introduction A group of precancerous lesion closely associated with the cervical cancer, which reflect the continuous process of the development of the cervical cancer 1.cin caused by virus infection rarely develop cervical cancer 2. ciN caused by multifactors may develop cervical cancer 3.TBS diagnosing system by ncl 1).atypical squamous cells, ABC (2).low-grade squamous intraepithelial lesion, LSIL 3.high-grade squamous intraepithelial lesion, HSIL LSIL means CiN L, rarely develop cervical cancer HSIL menas CiN II and ll, may develop cervical cancer

Introduction A group of precancerous lesion closely associated with the cervical cancer,which reflect the continuous process of the development of the cervical cancer. 1.CIN caused by virus infection rarely develop cervical cancer 2.CIN caused by multifactors may develop cervical cancer. 3.TBS diagnosing system by NCI (1).atypical squamous cells,ABC. (2).low-grade squamous intraepithelial lesion,LSIL. (3).high-grade squamous intraepithelial lesion ,HSIL. LSIL means CIN I,rarely develop cervical cancer. HSIL menas CIN II and III,may develop cervical cancer

Etiology HPV(human papillomaviruses) infection Epidemiologic risk factors for ciN 1, multiple sexual partners 2, high-risk sexual partner 3, early onset of sexual activity (<16) 4, a history of STDs(especially, HPV infection) 5,cigarette smoking 6, immunodeficiency 7, long-tem oral contraceptive pill use

Etiology  HPV(human papillomaviruses) infection  Epidemiologic risk factors for CIN: 1,multiple sexual partners 2,high-risk sexual partner 3,early onset of sexual activity(<16) 4,a history of STDs(especially, HPV infection) 5,cigarette smoking 6,immunodeficiency 7,long-tem oral contraceptive pill use

Cervical Histological Specialty (.primal squamo-columnar junction (1. physiologic squamo-columnar junction (ii). transformation zone (iv).squamous metaplasia (v).squamous epithelization

Cervical Histological Specialty (i).primal squamo-columnar junction (ii).physiologic squamo-columnar junction (iii).transformation zone (iv).squamous metaplasia (v).squamous epithelization

Pathology Cervical intraepithelial neoplasia(CiN degree I: ie, mild dysplasia, heterotype cells occupy lower 1/3 layer degree II: ie, moderate dysplasia, heterotype cells occupy the lower 2/3 layer degree I: ie, severe dysplasia and carcinoma in situ heterotype cells occupy whole layer

Pathology Cervical intraepithelial neoplasia(CIN) degree I: ie,mild dysplasia, heterotype cells occupy lower 1/3 layer degree II: ie,moderate dysplasia, heterotype cells occupy the lower 2/3 layer degree III: ie,severe dysplasia and carcinoma in situ, heterotype cells occupy whole layer

图108人类乳头状病毒和CN。图109CNⅢ和正常宫颈内膜

odor Q8900oDa lco opoo 正常上皮 不典型增生 原位癌 早期浸润癌 没润癌 图17-1宫颈癌的发展过程

Clinical findings t Usually no symptoms or signs t Early detection is extremely important

Clinical findings  Usually no symptoms or signs  Early detection is extremely important

Diagnosis Repeated cervical ctyology--TCT t Colposcopic examination Biopsy--the most reliable method to make diagnosis

Diagnosis  Repeated cervical ctyology--TCT  Colposcopic examination  Biopsy—the most reliable method to make diagnosis