山东大学：《口腔组织病理学》课程教学资源（课件讲稿）第十三章 口腔黏膜病 艾滋病的口腔表征 Oral Manifestations of AIDS

公少东子 180 SHANDONG UNIVERSITY 病的口腔表现 Oral Manifestations of aids

Department of Oral Pathology, Shandong University Oral Manifestations of AIDS 的口腔表现

rd们 anifesrazions of liDS 艾滋病又称获得性免疫缺陷综合征 (acquired immunodeficiency syndrome ADS),由人免疫缺陷病毒( human immunodefiency virus,HN)感染所致。 此病为致命性疾患,患者一旦染上HⅣV后, 约3个月内机体可产生相应的抗体,到出现 明显症状约3-5年左右。其死亡率几乎可达 100%。约半数患者其存活期仅一年半左右, 至今尚无理想的治疗方法。 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University 艾滋病又称获得性免疫缺陷综合征 (acquired immunodeficiency syndrome， AIDS)，由人免疫缺陷病毒 (human immunodeficency virus，HIV) 感染所致。 此病为致命性疾患，患者一旦染上HIV后， 约 3个月内机体可产生相应的抗体，到出现 明显症状约3--5年左右。其死亡率几乎可达 100%。约半数患者其存活期仅一年半左右， 至今尚无理想的治疗方法。 2

Oral Manifestations of fIDs 1990WHO国际合作中小 30种与HⅣV感染有关的口腔症状 分三组 与HⅣ感染密切相关 与HⅣ感染较少相关 与HV感染可能相关 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University 3 1990 WHO国际合作中心 30种与HIV感染有关的口腔症状 分三组

Oral Manifestations oF liDS esions Strongly associated with HIV infection Candidosis Erythematous Hyperplastic pseudomembranous Hairy leukoplakia(EBV HIV-associated periodontal diseases HIV-gingivitis Necrotizing ulcerative gingivitis HIV-periodontitis Necrotizing stomatitis Kaposis sarcoma Non-Hodgkin's Lymphoma Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University Lesions Strongly associated with HIV infection Candidosis Erytheomatous Hyperplastic peudomembranous Hairy leukoplakia (EBV) HIV-associated periodontal diseases HIV-gingivitis Necrotizing ulcerative gingivitis HIV-periodontitis Necrotizing stomatitis Kaposi’s sarcoma Non-Hodgkin’s Lymphoma 4

rd们 anifesrazions of liDS esions less commonly associated with HIV infection Atipical ulceration(oropharyngeal) Idiopathic thrombocytopenic purpura Salivary gland disorders Dry mouth, decreased salivary flow rate Uni-or bilateral swelling of major glands Viral infections(other than EBV Cytomegalovirus Herpes simplex virus Human papilloma virus Varicella-zoster virus Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University Lesions less commonly associated with HIV infection Atipical ulceration (oropharyngeal) Idiopathic thrombocytopenic purpura Salivary gland disorders Dry mouth, decreased salivary flow rate Uni- or bilateral swelling of major glands Viral infections (other than EBV) Cytomegalovirus Herpes simplex virus Human papilloma virus Varicella-zoster virus 5

Oral Manifestations of fIDs Lesions possibly associated with HIV infection Bacterial infections other than gingivitis/periodontitis Fungal infection other than candidosis Melanotis hyperpigmentation Neurologic disturbances Facial palsy Trigeminal neuralgia 6(今个 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University Lesions possibly associated with HIV infection Bacterial infections other than gingivitis/periodontitis Fungal infection other than candidosis Melanotis hyperpigmentation Neurologic disturbances Facial palsy Trigeminal neuralgia 6

Oral Manifestations of fIDs ●(一)念珠菌病 1.红斑型为红色病变区,无可能除去的白色斑点 或斑块。 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University （一）念珠菌病 1.红斑型 为红色病变区，无可能除去的白色斑点 或斑块。 7

Oral Manifestations oF liDS ●(一)念珠菌病 2.增生型为坚固而致密的白色斑块或针头大小的 小结节,附着于红色病变区。 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University （一）念珠菌病 2.增生型 为坚固而致密的白色斑块或针头大小的 小结节，附着于红色病变区。 8

Oral Manifestations of fIDs ●(一)念珠菌病 3.伪膜型为白色或黄色可除去的斑点或斑抉。 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University （一）念珠菌病 3.伪膜型 为白色或黄色可除去的斑点或斑块。 9

Oral Manifestations of fIDs ●(一)念珠菌病 4.口角炎型在口角出现鲜红色的裂沟。 Department of Oral Pathology, Shandong University 1901

Department of Oral Pathology, Shandong University （一）念珠菌病 4.口角炎型 在口角出现鲜红色的裂沟。 10