山东大学：《医学生理学 Medical Physiology》课程教学资源（PPT课件讲稿，人体生理学 Human Physiology）Chapter 11 Endocrine System I

gure he anatomy of some of the endocrine glands. (b)An islet of Langerhans within the pancreas Chapter 11 ENDOCRINE SYSTEM Pituitary Thyroid gland Parathyroid glands (behind thyroid gland Pancreas Ovary Creek Testis

1 Chapter 11, ENDOCRINE SYSTEM

Section 1 Introduction I. Concept of Hormone a hormone --chemical substance secreted into the interstitial fluids by one specialized cell or a group of cells --exert physiological control effect on other cells of the e body

2 Section 1 Introduction I. Concept of Hormone A hormone – --chemical substance --secreted into the interstitial fluids by one specialized cell or a group of cells --exert physiological control effect on other cells of the body

l Endocrine Vs Nervous syste

3 II. Endocrine vs. Nervous Syste

Nervous system exerts point-to-point control through nerves ° Similar to sending messages by conventional telephone electrical in nature and fast

4 Nervous system •exerts point-to-point control through nerves, •similar to sending messages by conventional telephone. •electrical in nature and fast

Hormones travel via the bloodstream to target cells .broadcasts its hormonal messages to essentially all cells by secretion into blood and extracellular fluid requires a receiver to get the message cells bear a receptor

5 Hormones travel via the bloodstream to target cells •broadcasts its hormonal messages to essentially all cells •by secretion into blood and extracellular fluid. •requires a receiver to get the message – •cells bear a receptor

III. Transportation of Hormones 1. Endocrine, or telecine T arget cel Secreting cell Blood vessel Target cell

6 III. Transportation of Hormones 1, Endocrine, or telecrine:

Transportation of hormones 2. Neuroendocrine Structural and functional relationships of the pituitary and Metos .lypowraiam c in the venta el ons in me conec ng stak na amic tycoon sea tract t pophyseal I typaphysei porta system Neurohypophysis storage arca fcr Secordary Posteror adenohypcpr yss Oxytocin ISH FSHLH Aa

7 2, Neuroendocrine: Transportation of Hormones

Transportation of hormones 3. Paracrine Receptor Secreting cell Target cell Not a target cell (no receptors)

8 3. Paracrine Transportation of Hormones

ep AdenohypophysIs - hypophyseal Pituita hypophysis vessels ACTH ACTH FSH ADH arg Gut horr Telecrin Autocrine Intracrine Solinocrine

Solinocrine Autocrine Intracrine

IV Classification of hormones 1. Proteins and polypeptides, including hormones secreted by anterior and posterior pituitary gland pancreas(insulin and glucagon) parathyroid gland(parathyroid hormone) many others Insulin [51 amino acids

10 IV. Classification of Hormones 1. Proteins and Polypeptides, including hormones secreted by anterior and posterior pituitary gland pancreas (insulin and glucagon) parathyroid gland (parathyroid hormone) many others