慢性疼痛（PPT讲稿）Chronic Pain

Chronic Pain Dr Mc chu Anaesthesia and Intensive Care PWH

Chronic Pain Dr. MC Chu Anaesthesia and Intensive Care PWH

Agenda Start at acute pain Un-veil the complexity of chronic pain In second part we will try to treat them

Agenda Start at acute pain Un-veil the complexity of chronic pain In second part we will try to treat them

Lets start with acute pain Tissue damage Site and intensity correlation Gets better with healing(self limiting

Let’s start with acute pain Tissue damage Site and intensity correlation Gets better with healing (self limiting)

Case 1 A man with a pain in his right leg “ Are you sure it is the right leg?

Case 1 A man with a pain in his right leg “Are you sure it is the right leg?

Case 1 Aman with a pain in his right leg How does it feel like?

Case 1 A man with a pain in his right leg How does it feel like?

Case 1 Aman with a pain in his right leg And any other abnormalities?

Case 1 A man with a pain in his right leg And any other abnormalities?

Case 1 Aman with a pain in his right leg What causes it?

Case 1 A man with a pain in his right leg What causes it?

Remarks from case 1 Chronic pain is not prolonged acute pain Acute Pain Chronic Pain Glutmate Closed. Terminal Channel Guanyl 8 NMDA AMPA PKC Na·K No Nitc Oxide Gos Gene

Remarks from Case 1 Chronic pain is not prolonged acute pain

Remarks from case 1 Pathophysiology is different from acute pain Sensitization Reduced pain threshold(hyperalgesia) Non-painful stimulus(allodynia)

Remarks from Case 1 Pathophysiology is different from acute pain Sensitization Reduced pain threshold (hyperalgesia) Non-painful stimulus (allodynia)

Remarks from case 1 Pathophysiology is different from acute pain Neuropathic pain Site Character Timing More than that

Remarks from Case 1 Pathophysiology is different from acute pain Neuropathic pain Site Character Timing More than that…