复旦大学：《儿科学》课程教学资源（PPT课件讲稿）第五讲 先天性心脏病概论

Cardiovascular diseases in Children ( Conspectus HUANG Guoying(黄国英) Department of Pediatrics Fudan University shanghai Medical school Childrens Hospital of Fudan University

HUANG Guoying（黄国英） Department of Pediatrics Fudan University Shanghai Medical School Children’s Hospital of Fudan University Cardiovascular Diseases in Children （Conspectus ）

The Aim of this class To understand the classification of chD To know well the embryological development of heart, causes of CHD and its pathogenesis To know well the approaches of evaluation of CHD To know the characteristics of fetal circulation changes after birth To have a general idea about cardiovascular diseases in children, and the principle of treatment of chd

The Aim of This Class • To understand the classification of CHD • To know well the embryological development of heart, causes of CHD and its pathogenesis • To know well the approaches of evaluation of CHD • To know the characteristics of fetal circulation & changes after birth • To have a general idea about cardiovascular diseases in children, and the principle of treatment of CHD

A Children's Hospital 摄于1947年赴美参加国际儿释 公议 Founded in 19 52 Professor chen cuizhen

Children’s Hospital Founded in 1952 Professor CHEN Cuizhen

Cardiovascular Diseases in Children Congenital heart disease Viral myocarditis Rheumatic heart disease Cardiomyopathy · Kawasaki Disease Arrhythmia Congestive heart failure Pericarditis Infective endocarditis Etc

Cardiovascular Diseases in Children • Congenital heart disease • Viral myocarditis • Rheumatic heart disease • Cardiomyopathy • Kawasaki Disease • Arrhythmia • Congestive heart failure • Pericarditis • Infective endocarditis • Etc…

Embyological Development of Heart Formation of primitive heart tube Looping of primitive heart tube Formation of endocardial cushion Formation of interatrial septum Formation of interventricular septum Septation of aortic and pulmonary arteries

Embyological Development of Heart • Formation of primitive heart tube • Looping of primitive heart tube • Formation of endocardial cushion • Formation of interatrial septum • Formation of interventricular septum • Septation of aortic and pulmonary arteries

Formation and Looping of Primitive heart tube b33 小 鲁 地心情 省琳转 压长 I.MM E $m-r 心晓的早期发育

Formation and Looping of Primitive Heart Tube

Formation of endocardial cushion AV canal posterior right av orifice ∴∴‘1 anterior left av orifice

Formation of Endocardial Cushion AV canal posterior right AV orifice anterior left AV orifice

Formation of endocardial cushion as LA RA EC RV IVS

Formation of Endocardial Cushion

Septation of Atria and Ventricles Interventricular ostium primum ostium secundum foramen foramen ovale 3 10 8 8 胚胎第3周 胚胎第4周 胚胎第5-6周 胚胎第7-8周 I= LA 2=LV 3=RA 4=RV septum primum 6=septum secundum 7= endocardial cushion,9=ventricular septa

Septation of Atria and Ventricles ostium primum 1＝LA 胚胎第3周 胚胎第4周 胚胎第5-6周 胚胎第7-8周 2＝LV 3＝RA 4＝RV 5＝septum primum 6＝septum secundum 7＝ endocardial cushion ostium secundum foramen ovale 8,9＝ventricular septa Interventricular foramen

Septation of Atria

Septation of Atria