复旦大学：《传染病学 Infectious Disease》课程教学资源（MBBS）教学课件（英文）布鲁斯氏杆菌病 Brucellosis

BRUCELLOSI Jialin jin Fudan University Huashan Hospital Department of infectious diseases Nov.2014

Jialin Jin Fudan University Huashan Hospital Department of infectious diseases Nov. 2014

BRUCELLOSIS > It is term used as a convenient description for all phases of the disease caused by a bacteria called brucella Many names have been applied to it as 1. Malta fever 2. Mediterranean fever 3. Gibraltar or rock fever 4. Undulant fever

 It is term used as a convenient description for all phases of the disease caused by a bacteria called Brucella. Many names have been applied to it as: 1. Malta fever 2. Mediterranean fever. 3. Gibraltar or rock fever 4. Undulant fever

人间布病流行情况 ncidence of human brucellosis Annual indidence of brucellosis per 1000000 population >500 口90-500c%5 ■10-50 □ Possbly endemic no data Source: The new global map of human brucellosis. Lancet, 2006

人间布病流行情况

19912011年全国布病时间分布特点 INCIDENCE OF BRUCELLOSIS IN CHINA 发病数(例) 发病率(1/10万) 45000 38151 例 285/10万 40000 35000 30000 25000 20000 15000 10000 □发病数一发病率(1/10万) 05 5000

1991-2011年全国布病时间分布特点 INCIDENCE OF BRUCELLOSIS IN CHINA

2004-2011年全国布病报告病例地区分布特点 全国布病疫情空间上呈现阶梯式分布,梯间 差异较大,病例相对集中的特点 2004-2011年报告病例数居全国前5位的省份 分别是内蒙古、山西、黑龙江、河北、吉林 报告布病181924例,占全国报告病例总数的 吉海省 城看味 8912%。 自区 四川省 2004年 飞今州的 合计报告发病数 ok 00至90300(5) 100至99 门 报告发病率(/10万) 433 00001

2004-2011年全国布病报告病例地区分布特点

Brucellosis Common classical zoonotic disease of worldwide distribution The genus Brucella consists of 7 species, four of which cause human brucellosis

 Common classical zoonotic disease of worldwide distribution .  The genus Brucella consists of 7 species, four of which cause human brucellosis

Organism Animal Reservoir Geographic Distribution B melitensis Goats Mediterranean,Asia atin America, parts of Sheep, and some southern camels European countries B abortus Cows, buffalo, camels, Worldwide yaks South america B suis Pigs(biotype 1-3) Southeast Asia, United States Brucella canis Canines Cosmopolitan

Organism Animal Reservoir Geographic Distribution B melitensis Goats, sheep, camels Mediterranean, Asia, Latin America, parts of and some southern European countries B abortus Cows, buffalo, camels, yaks Worldwide B suis Pigs (biotype 1-3) South America, Southeast Asia, United States Brucella canis Canines Cosmopolitan

Reservoir Br。 Melitensis→ Goats, Sheep, camels Most widespread Most virulent

Reservoir: Br. Melitensis → Goats , Sheep , camels. Most widespread Most virulent

Reservoir. Br. Abortus Cattle and camels Less virulent

Br. Abortus → Cattle and camels . Reservoir: Less virulent

Reservoir. Br.Suis→Pig Less virulent

Reservoir: Less virulent