武汉大学生命科学学院：《分子生物学》英文版 CHAPTER 21 Model Organisms

Welcome each of You to My molecular Biology class 博来字 Wuhan University

Welcome Each of You to My Molecular Biology Class

Molecular Biology of the Gene 5/E --Watson et al. (2004) Part I: Chemistry and Genetics Part: Maintenance of the genome Part ll: Expression of the Genome Part IV: Regulation Part v: methods 3/22/05 Wuhan University

Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods 3/22/05

Part v: Methods ch 20: Techniques of Molecular Biology ch 21: Model Organisms

Part V: Methods Ch 20: Techniques of Molecular Biology Ch 21: Model Organisms

Molecular iology course CHAPTER 21 Model organisms 博字 Wuhan University

CHAPTER 21 Model Organisms •Molecular Biology Course

Model organisms > Fundamental problems are solved in the simplest and most accessible system in which the problem can be addressed >These organisms are called model organisms

Model Organisms ➢Fundamental problems are solved in the simplest and most accessible system in which the problem can be addressed. ➢These organisms are called model organisms

Some Important Model Organisms Escherichia coli and its phage(the T Phage and phage n) > Baker's yeast Saccharomyces cerevisiae >The nematode caenorhabditis elegans >The fruit fly Drosophila melanogaster >The house mouse mus musculus

Some Important Model Organisms ➢Escherichia coli and its phage (the T phage and phage λ) ➢Baker’s yeast Saccharomyces cerevisiae ➢The nematode Caenorhabditis elegans ➢The fruit fly Drosophila melanogaster ➢The house mouse Mus musculus

Features of Model systems The availability of powerful tools of traditional and molecular genetics. The study of each model system attracted a critical mass of investigators. (Ideas, methods, tools and strains could be shared)

Features of Model Systems ◼The availability of powerful tools of traditional and molecular genetics. ◼The study of each model system attracted a critical mass of investigators. (Ideas,methods, tools and strains could be shared)

HOW to choose a model organism? It depends on what question is being asked. When studying fundamental issues of molecular bIologY, sImpler unicellular organisms or viruses are convenient, For developmental questions, more complicated organisms should be used

HOW to choose a model organism? It depends on what question is being asked. When studying fundamental issues of molecular biology, simpler unicellular organisms or viruses are convenient. For developmental questions, more complicated organisms should be used

CHATER 15 The Genetic Code Model 1s BACTERTOPHAGE 5/08/05 @博共字 Wuhan Universit

Model 1: BACTERIOPHAGE CHAPTER 15 The Genetic Code 5/08/05

Bacteriophage (viruses) >The simplest system >Their genomes are replicated only after being injected into a host cell. >The genomes can recombine during these infections

Bacteriophage (Viruses) ➢The simplest system ➢Their genomes are replicated only after being injected into a host cell. ➢The genomes can recombine during these infections