中国医科大学：《病理学》课程教学课件（PPT讲稿，英文）Chapter 3 Hemodynamic diosrder

ChapterⅢHemodynamicDisorderSection 1. Hyperemia and Congestion

Chapter Ⅲ Hemodynamic Disorder Section 1. Hyperemia and Congestion

To thoracic duct and eventuallyto left subclavianveinIncreasedinterstitialfluidpressureHydrostaticpressurePlasma colloidosmoticpressureVenousendCAPILLARYBEDArterialend

一. Arterial hyperemia1. Definition:Increasedvolumeof arterialinflow山an organ or tissue (hyperemia2. Common types:(1) Physiologic: exercise -→ skeletal muscle(2)Pathologic:atthe fociof inflammation(3) Hyperemia after reducing pressure

一 . Arterial hyperemia 1. Definition: Increased volume of arterial inflow in an organ or tissue (hyperemia) 2. Common types: (1) Physiologic: exercise skeletal muscle (2) Pathologic: at the foci of inflammation (3) Hyperemia after reducing pressure

3.Sequelae:(l)Restore:ifcausesabated(2)Hemorrhage:hypertension,AS二、CongestionResulting from an isolate venous obstructionaccumulation of blood in veinlet and capillary

3. Sequelae : (1) Restore: if causes abated (2) Hemorrhage: hypertension , AS 二、Congestion Resulting from an isolate venous obstruction accumulation of blood in veinlet and capillary

Etiology(一)11. Veins being pressed:Tumor → press local veinpseudolobulehepatic sinus2.Venous obstruction: thrombosis3. Heart failure:left→pulmonarycongestionright →hepatic congestion

(一) Etiology 1. Veins being pressed: Tumor → press local vein pseudolobule →hepatic sinus 2. Venous obstruction: thrombosis 3. Heart failure: left →pulmonary congestion right →hepatic congestion

(二) Lesions and results1.Hydrostatic pressurecongestive edema, hemorrhage2. Chronic hypoxiaatrophy or degenerationfibrosis,sclerosis

(二) Lesions and results 1. Hydrostatic pressure congestive edema, hemorrhage 2. Chronic hypoxia atrophy or degeneration fibrosis, sclerosis

(三)Congestion of importantorgans1.Pulmonary congestion(acute,chronic)(l) Cause: left heart failure(2)Morphology:DGross:volumeweighttdark redcut surfaceconsolidated

(三) Congestion of important organs 1. Pulmonary congestion(acute,chronic): (1) Cause: left heart failure (2) Morphology: ① Gross: volume↑ weight↑ dark red cut surface consolidated

② LM (acute,chronie) :Aalveolar septacapillary engorged with bloodbecome thickenedfibrosisedema fluidAlveolar spacesheart failure cellshemorrhageBrown induration: long period congestion, texturebecome solid and show brown appearance

② L M (acute,chronic) : Aalveolar septa capillary engorged with blood become thickened fibrosis Alveolar spaces edema fluid heart failure cells hemorrhage Brown induration: long period congestion, texture become solid and show brown appearance

Chronic pulmonarycongestion

Chronic pulmonary congestion

Heart failure cells: Hemosiderin- laden Mp

慢性肺淤血 Heart failure cells: Hemosiderin- laden Mφ