扬州大学：《生理学》课程教学课件（讲稿）第五章 呼吸生理 Respiration Physiology

Respiratory PhysiologyHuaDaidaihua@yzu.edu.cnMedicalSchoolYangzhou University

Respiratory Physiology Hua Dai daihua@yzu.edu.cn Medical School Yangzhou University

揚州大学YANGZHOUUNIVERSITY2019 novel coronavirus

2019 novel coronavirus

揚州大学YANGZHOUUNIVERSITYChestCTscanofthepatientChestCTscanoftheTheCTscanrevealedextensivehealthy lunginfiltrates inthe lungwithpleuraleffusion. (white lung)

Chest CT scan of the patient. The CT scan revealed extensive infiltrates in the lung with pleural effusion. (white lung) Chest CT scan of the healthy lung

RespirationDefinition:- the bodily processes involved in exchange of oxygen(O2) and carbon dioxide (CO2) between an organism andthe environment.Consist of-Inspiration:the inhalation of airinto the lung. Obtain O, from theexternalenvironment-Expiration:breathingout.RemoveCO, from the body

Definition: – the bodily processes involved in exchange of oxygen ( O2 ) and carbon dioxide (CO2 ) between an organism and the environment. Respiration Consist of – Inspiration: the inhalation of air into the lung. Obtain O2 from the external environment. – Expiration: breathing out. Remove CO2 from the body

Respiratory systemLungsBronchiAlveoliBronchidliThe relaxation/contraction of circular smooth muscle liningthese“airways”determineshoweasilyairflowcan occurMost gas exchange occurs inthe alveolar sacs (8 X 106)

Respiratory system The relaxation/contraction of circular smooth muscle lining these “airways” determines how easily airflow can occur. Most gas exchange occurs in the alveolar sacs (8×106 )

The goals of respirationBeginAtmosphereVentilationAlveoli02CO2GasexchangeTo provide oxygen toBlood flowBlood flowthe tissuesPulmonarycirculationRightLeftGastransportTo remove carbonheartheartSystemiccirculationdioxide.GasexchangeOCO2Cells5Cellularrespiration

The goals of respiration To provide oxygen to the tissues To remove carbon dioxide

Chapter5 RespirationphysiologySection 1 Pulmonary ventilationSection 2 Gases exchangeSection 3 Gases transport in bloodSection 4 Regulation of respiration

Chapter 5 Respiration physiology Section 1 Pulmonary ventilation Section 2 Gases exchange Section 3 Gases transport in blood Section 4 Regulation of respiration

揚州大学YANGZHOUUNIVERSITYThree majorfunctional events of respiration1.External InspirationoodCirculationTissue,CapillaryCellLungO2O2CO,coO022. Gas Transport in BloodGasExchangePulmonary3.Internal InspirationGasExchangGas TransportintheTissueVentilationinthe LunginBloodInternalExternalInspirationInspiration

Three major functional events of respiration Internal Inspiration External Inspiration 2. Gas Transport in Blood 3. Internal Inspiration 1. External Inspiration

Section1PulmonaryVentilationDefinition:Nasal cavityNostrilPharynxThe process of moving airOral cavity-Tracheainto and out of the lungs.LarynxRightmain(primary)bronchusLeftmainRight lung(primary)bronchusThebasisofthewholeBase ofleft lungprocess of respiratory.DiaphragmCopyrighte2009 Pearson Educatson; Inepublishing ss PearsonBenjamin Cummings

Definition: The process of moving air into and out of the lungs. The basis of the whole process of respiratory. Section 1 Pulmonary Ventilation

I. Structures of pulmonary ventilationNasal cavityNostrilPharynxOralcavityTracheaLarynx1.ThoraxRight main(primary)bronchusLeftmainRight lung(primary)bronchusBaseofleft lungDiaphragmcopynA closed compartment, that is bounded at the neck bymuscles andconnective tissue and completely separatedfromtheabdomenbythediaphragm

A closed compartment, that is bounded at the neck by muscles and connective tissue and completely separated from the abdomen by the diaphragm. 1. Thorax I. Structures of pulmonary ventilation