上海交通大学：《有机化学》教程教学资源（英文讲稿）12 Amines Amines-Organic Nitrogen Compounds

445 12. Amines Amines-Organic Nitrogen Compounds

12. Amines p.445 Amines – Organic Nitrogen Compounds

uC r(h) R(H

N C R(H) R'(H) .. N N H

CHoCHoNH chocolate Unpleasant CH33N “fshy” odors

CH2CH2NH2 chocolate (CH3 )3N Unpleasant “fishy” odors

Vitamine coined in 1912 CHOH HO+H CH3 HO+H OH N HO+H s CI H3C NH NH H2C Vitamin b Vitamin b O H COH COHn V B3;V v bus HOC 0 烟酸;烟酰胺 DQQ

Vitamine coined in 1912 N CO2HN CO2H HO2C O O H DQQ CH2OH HO H HO H HO H N N NH N O H O 3C H3C Vitamin B2 + Cl￾Vitamin B1 N N N S NH2 CH3 OH CH3 V B3 ; V B6 ; V B12; 烟酸; 烟酰胺

Polyamines H2N NH2 Putrescine(腐胺) HONY NH2 Spermidine(亚精胺)

Putrescine(腐胺) Spermidine(亚精胺) H2N NH2 H2N N NH2 H Polyamines :

H H3C CHbNHCH3 CO,Me Cocaine epinephrine 0COPh可卡因 OH 肾上腺素 H OH H H HO H H3o CO H H H Koumine Cinchonidine 钩吻素子 喹咛

N CO2Me OCOPh H H H3C Cocaine 可卡因 OH OH C HO H CH2NHCH3 Epinephrine 肾上腺素 N N O H H H CH3 Koumine 钩吻素子 H H H HO N N H3CO Cinchonidine 喹咛

CH=CHCH -NEC=S isothiocyanate(未味) + NH3 OH cO, O 0 H L-tricholomic acid Indigo(靛 口蘑氨酸) 蓝)

CH2 CHCH2 N C S Allyl isothiocyanate(芥末味) L-tricholomic acid (口蘑氨酸) N O O CO2 - NH3 + H N N H H O O Indigo(靛 蓝）

tetramine N 毒鼠强 NH S Cl OH CHr-cH-n-p 00 杀鼠灵 毒鼠膦

N S N N S N O O O O tetramine 毒鼠强 CH N P S Cl Cl CH3 NH O O OH O 杀鼠灵 毒鼠膦

N NH 渗入头发H2O2 聚合 N 12 NH NHo 色酚 N N

NH2 NH2 NH NH 渗入头发 H2O2 聚合 N N N N NH2 H2N H H H2O2 色酚

12. 1 Naming Amines #0 Alkyl-substituted (alkylamines) or aryl-substituted(arylamines) Classified 1(RNH2), methyl CH3NH2), 2(R2NH), 3(RN) CH CH3 CH Hg3C-C-OH HOC-N H3C-C-NH2 CH CHs CH tert-Butyl alcohol Trimethylamine tert-Butylamine (a tertiary alcohol) (a tertiary amine) (a primary amine) ②204 Thomson/ Brooks Cole

12.1 Naming Amines • Alkyl-substituted (alkylamines) or aryl-substituted (arylamines) • Classified: 1° (RNH2 ), methyl (CH3NH2 ), 2° (R2NH), 3° (R3N) P.446