大连医科大学：《组织胚胎学》课程教学课件（英文讲稿）S-embryology-development of digestive and respiratory system

Development of Digestive andRespiratory Systems

Development of Digestive and Respiratory Systems

Learning aimsthe derivatives of the individual pharyngeapouches the growth of the midgut loop. division of cloacacongenital Malformations of digestive andrespiratory system

Learning aims • the derivatives of the individual pharyngeal pouches • the growth of the midgut loop • division of cloaca • congenital Malformations of digestive and respiratory system

I Development of DigestiveSystemII Development of Respiratory SystemPrimordium -- The primitive gutngealme

Primordium - The primitive gut ⅠDevelopment of Digestive System Ⅱ Development of Respiratory System

1. Foregut2. Midgut3. HindgutPharyngealpouchesPharyngeal gutTracheobronchialdiverticulumEsophagusEsophagusStomodeumStomachLiverHeartbulgeGallbladderPancreasVitelline duct-PrimitiveAllantoisintestinalloopUrinarybladderCloacaCloacal-HindgutmembraneAB

1. Foregut 2. Midgut 3. Hindgut

1. Development of foregut1.1 upper foregut ----embryonicpharynx

1. Development of foregut 1.1 upper foregut - embryonic pharynx

1.1.1. Derivatives of PharyngealPouchesMaxillaryprocess.1) 1st pouchMandibularprocessPrim.tympanicPharyngealLateral → tympanicPharyngealcavitypouchescleftscavityExt.PharyngotympanicauditorytubemeatusMedial-PalatinetonsilpharyngotympanictubeParathyroidgland (inf.)ThymusParathyroidCervicalgland (sup.)sinusUltimo-branchialEpicardialbodyridgeB

1.1.1. Derivatives of Pharyngeal Pouches 1) 1st pouch Lateral → tympanic cavity Medial → pharyngotympanic tube

2)2nd pouchtonsillar fossa, surface epithelium of palatinetonsilMaxillary3) 3rd pouchprocessMandibularprocessDorsal part -PrimtympanicPharyngealPharyngealcavityinferiorcleftspouchesExt.-PharyngotympanicauditorytubeparathyroidsmeatusPalatinetonsilVentral part Parathyroidgland (inf.)thymusThymusParathyroidCervicagland (sup.)Both migratesinusUltimo-branchialEpicardialbodyridgecaudally.B

3) 3rd pouch Dorsal part → inferior 2) 2nd pouch → tonsillar fossa, surface epithelium of palatine tonsil inferior parathyroids Both migrate caudally. Ventral part → thymus

4) 4th pouchDorsal →superior parathyroidsVentral →degeneratesMaxillaryprocessMandibularprocessPrim.tympanicPharyngealPharyngeal5)5thpouch→cavitypouchescleftsExt.Pharyngotympanicauditorytubeultimobranchial bodymeatusPalatinetonsilparafollicular cellsParathyroidgland (inf.)(in thyroid)ThymusParathyroidCervicalgland(sup.)sinusUitimobranchialEpicardialbodyridgeB

4) 4th pouch Dorsal → superior parathyroids. Ventral → degenerates 5) 5th pouch → ultimobranchial body →parafollicular cells (in thyroid)

1.1.2 development of thyroid原始咽 a median thickening ofthe endoderm on thefloor of the embryonic甲状舌管退化pharynx甲状腺a bilobular sacculationthyreoglossal ductforamen cecum胸腺See flashPersistence ofthyreoglossalduct?

1.1.2 development of thyroid • a median thickening of the endoderm on the floor of the embryonic pharynx • a bilobular sacculation • thyreoglossal duct • foramen cecum Persistence of thyreoglossal duct? See flash

Brief summaryPharyngotympanic tubePrimarytympanic-Ventral sidecavityofpharynxExt.auditoryForamencecummeatusPalatinetonsilSup.parathyroidgland(from4thpouch)-ThyroidInf.parathyroidglandgland(from3rdpouch)Uitimobranchialbody-ForegutThymusSeeflash

Brief summary See flash