大连医科大学：《组织胚胎学》课程教学课件（英文讲稿）S-embryology-development of urogenital system

Development ofthe Urogenital System

Development of evelopment of the Urogenital System Urogenital System

LearningaimsDevelopment of metanephrosDerivatives of urogenital sinusThestepsthatoccurinthedifferentiation of the testes and ovariesCongenital malformations of urogenitalsystem

Learning aims • Development of metanephros • Derivatives of urogenital sinus • The steps that occur in the differentiation of the testes and ovaries • Congenital malformations of urogenital system

Primordia:Intermediate mesodermyolk sacJendodermstalkextra10embryonicmesoderm3

Primordia: Intermediate mesoderm

中肾峭Mesonephric ridge尿生殖嵋Urogenital生殖腺ridgeGonadal ridgeCervicalpart→nephromereCaudal part→nephrogeniccords生殖结节Genital tubercleUrogenitalridgegonadal ridge mesonephricridge(inner)(outer)

Cervical part → nephromere Caudal part → nephrogenic cords Urogenital ridge gonadal ridge (inner) mesonephric ridge (outer)

?横断面Transection中肾管Mesonephricduct

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I Development ofUrinary System1. Development of Kidney and UreterMthreestages:Pronephrostransitory structureMesonephrosMetanephros→definitive kidney

1. Development of Kidney and Ureter ⅠDevelopment of Urinary System three stages: Pronephros Mesonephros Metanephros transitory structure definitive kidney

1.1Pronephros (forekidney):Nephromere → pronephric tubules and duct -pronephros → degenerates.VestigalpronephricsyslemMesonephrictubulesMesonephricsystemMesonephricductUreteric budMetanephricsystem

1.1 Pronephros (forekidney): Nephromere → pronephric tubules and duct → pronephros → degenerates

1.2Mesonephros:1) mesonephric ridge → mesonephric ductVestigalpronephricsystemMesonephrictubulesMesonephricsystemIntestinalloop-MesonephrosMesonephricductGonad--MesonephricductUreteric budMetanephricsystem

1.2 Mesonephros: 1) mesonephric ridge → mesonephric duct

2)Mesonephrictubules→mostdisappear1.Neuraltube5.Intestinaltube9.Mesonephric duct (Wolffianduct)10.Mesonephrictubule11.Urogenital ridge

1.Neural tube 5.Intestinal tube 9.Mesonephric duct (Wolffian duct) 10.Mesonephric tubule 11.Urogenital ridge 2) Mesonephric tubules → most disappear

1.3metanephros:definitivekidney1)Primordia: ureteric bud and metanephricblastemaHindgutMesonephrictissueAllantois-MesonephricductUrorectalseptumUretericCloaca-budMetanephricblastema

1.3 metanephros: definitive kidney 1) Primordia: ureteric bud and metanephric blastema