《病原生物学》课程PPT教学课件（寄生虫学）刚地弓形虫（Toxoplasma gondii）

刚地弓形虫Toxoplasma gondii简称弓形虫，弓浆虫。寄生于人和许多种动物的有核细胞，引起人畜共患的弓形虫病(toxoplasmosis)。特别在宿主免疫功能低下时致病，属机会致病原虫(opportunisticprotozoa)

简称弓形虫，弓浆虫。寄生于人和许多 种动物的有核细胞，引起人畜共患的弓 形虫病(toxoplasmosis )。特别在宿主免 疫功能低下时致病，属机会致病原虫 (opportunistic protozoa) 刚地弓形虫 （Toxoplasma gondii）

一、形态在发育过程中，有5种形态。滋养体在有核细胞内，假包囊内滋养体叫速殖子tachyzoite包囊cyst 大量虫体分泌物形成的囊状结构，包囊内滋养体叫缓殖子bradyzoite卵囊oocyst内含2个孢子囊，每个孢子囊内含4个子孢子。裂殖体配子体

一、形态 在发育过程中，有5种形态。 滋养体 在有核细胞内，假包囊内滋养体叫速殖子tachyzoite 包囊 cyst 大量虫体分泌物形成的囊状结构，包囊内滋养体 叫缓殖子bradyzoite 卵囊oocyst 内含2个孢子囊，每个孢子囊内含4个子孢子。 裂殖体 配子体

在分裂中假包囊游离丁体液的速殖子中的速殖子包裹

Toxoplasmagondii in the bronchoalveolarlavage(BAL)material from an HIv infected patient. Numeroustrophozoites(tachyzoites)can be seen, which are typicallycrescent shaped with a prominent,centrally placednucleus. Most of the tachyzoites arefree, some are stillassociatedwithbronchopulmonarycells

Toxoplasma gondii in the bronchoalveolar lavage (BAL) material from an HIV infected patient. Numerous trophozoites (tachyzoites) can be seen, which are typically crescent shaped with a prominent, centrally placed nucleus. Most of the tachyzoites are free, some are still associated with bronchopulmonary cells

microscopical features of tachizoites of Toxoplasma gondiand peritoneal macrophages of mouse in peritoneal exudate.(SEM)

microscopical features of tachizoites of Toxoplasma gondii and peritoneal macrophages of mouse in peritoneal exudate. (SEM)

microscopical features of tachizoites of Toxoplasma gondiiand peritoneal macrophages of mouse in peritoneal exudate(SEM)

microscopical features of tachizoites of Toxoplasma gondii and peritoneal macrophages of mouse in peritoneal exudate. (SEM)

T. gondii: transmision electronmicroscopic pictureLongitudinal section of anendozoid

T. gondii: transmision electron microscopic picture. Longitudinal section of an endozoid

T. gondi: cross-section through an endozoid in an advanced stageof endodiogeny. The daugther cells appear to be surrounded.Ineach of these news cells there are two round bodies that lengthenformingthefirstrhoptries

T. gondii: cross-section through an endozoid in an advanced stage of endodiogeny. The daugther cells appear to be surrounded. In each of these news cells there are two round bodies that lengthen forming the first rhoptries

Toxoplasmagondiiin tissuefroma cat

Toxoplasma gondii in tissue from a cat

toxoplasmic pseudocyst within an inflammatorytissue reaction(H&Estain)

toxoplasmic pseudocyst within an inflammatory tissue reaction. (H&E stain)