《人体寄生虫学 Human parasitology》课程教学课件（讲稿）Lectures 5.Schistosoma

Review Paragonimus westermanigutmehlis' glandovarytestisvitellariaexcretionduct

Review Paragonimus westermani

Life cycle (summary1. Infective stage: metacercaria2. Infective route: by mouth3. Site of inhabitation: lungs4. Intermediate hosts: 1st int. host is melania snail. 2nd int.hosts are crab and crayfish5. Reservoir hosts: carnivores such as tiger, lion, wolffox, dog, leopard, cat, etc

Life cycle (summary) 1. Infective stage: metacercaria 2. Infective route: by mouth 3. Site of inhabitation: lungs 4. Intermediate hosts: 1 st int. host is melania snail. 2 nd int. hosts are crab and crayfish. 5. Reservoir hosts: carnivores such as tiger, lion, wolf, fox, dog, leopard, cat, etc

Clinicalmanifestation:1)Pulmonary type; (2) Brain type; 3)Abdominal type;4)SubcutaneoustypeDiagnosis: find egg in sputum and stoolTreatment:Drug of choice is praziqantel.Other effectivedrugis bithionol

• Clinical manifestation: 1)Pulmonary type; (2) Brain type; 3)Abdominal type; 4)Subcutaneous type Diagnosis: find egg in sputum and stool Treatment: Drug of choice is praziqantel. Other effective drug is bithionol

SchistosomesSp140(Blood flukes)

Schistosomes p140 (Blood flukes)

Schistosoma(裂体吸虫)They belong to Genus Schistosoma, live in blood vesseland cause schistosomiasis.People call them blood flukes.There are four species infecting human body. They are:SchistosomajaponicumSchistosomamekongi（湄公血吸虫）Schistosomahaematobium（埃及血吸虫）Schistosomamansoni（曼氏血吸虫）

Schistosoma(裂体吸虫) They belong to Genus Schistosoma, live in blood vessel and cause schistosomiasis. People call them blood flukes. There are four species infecting human body. They are: Schistosoma japonicum Schistosoma mekongi (湄公血吸虫) Schistosoma haematobium（埃及血吸虫） Schistosoma mansoni（曼氏血吸虫）

（日本血吸虫）1. Schistosoma japonicumIt is prevalent in Far East.In china, it is prevalent in Yangtze valley and south of Yangtzeexcept Guizhou Province.The adults live in the portal vein system, causing liver cirrhosis（肝硬化）and portal veinhypertension syndrome（门脉高压征候群）

1. Schistosoma japonicum（日本血吸虫） It is prevalent in Far East. In china, it is prevalent in Yangtze valley and south of Yangtze except Guizhou Province. The adults live in the portal vein system, causing liver cirrhosis （肝硬化）and portal vein hypertension syndrome（门脉高压 征候群）

2. Schistosoma mansoni（曼氏血吸虫）is distributed in Africa and focal area in LatinAmericaLives in the portal and hemorrhoidal vein plexus, causing stoolwith fresh blood, liver cirrhosis and portal vein hypertension

2. Schistosoma mansoni（曼氏血吸虫） is distributed in Africa and focal area in Latin America. Lives in the portal and hemorrhoidal vein plexus, causing stool with fresh blood, liver cirrhosis and portal vein hypertension

3.Schistosoma haematobium（埃及血吸虫）widely spreads in Africa, chiefly in Nile River valleyThe adults live in the vesical and pelvic plexus causingrenalfailureterminalpainlesshaemuresis,complicated by the ureter obstruction

3. Schistosoma haematobium（埃及血吸虫） widely spreads in Africa, chiefly in Nile River valley. The adults live in the vesical and pelvic plexus causing painless terminal haemuresis, renal failure complicated by the ureter obstruction

4.Schistosoma mekongi (湄公血吸虫)It is merely distributed in Mekong River ValleyjaponicumresemblesSchitosomaexceptintermediate host

4. Schistosoma mekongi (湄公血吸虫) It is merely distributed in Mekong River Valley, resembles Schitosoma japonicum except intermediate host

GeographicDistribution of SchistosomiasisAffected CountriesS.haematobiumS.japonicumS.mansoniS.mansoniandS.haematobiumNone4000040008000MilesRegenatDistibutionofSebistoremiasis10RegionCountriea AffecteSouthAnefesINorthem AfricaSouth America3outhernArics9NorthernAfricaWelternAtic19SouthernAfricaCaribbean17Western AfricaMidtieEant6Carsbbean9Middie EastCounpries Anested