中国医科大学附属第一医院：《内科学》课程教学资源（PPT课件讲稿，双语版）Coronary Heart Disease（Ischemic Heart Disease）

Coronary Heart Disease (Ischemic Heart Disease) Bai xiaojuan

Coronary Heart Disease (Ischemic Heart Disease) Bai Xiaojuan

Content. l。 Atherosclerosis 2. Angina pectoris 3. Myocardial infarction

Content: 1. Atherosclerosis 2. Angina pectoris 3. Myocardial infarction

Definition CHD is defined as myocardial impairment due to an imbalance between coronary blood flow and myocardial requirements caused by changes in the coronary circulation a Coronary atherosclerosis b Coronary spasm

CHD is defined as myocardial impairment due to an imbalance between coronary blood flow and myocardial requirements caused by changes in the coronary circulation a.Coronary atherosclerosis b.Coronary spasm Definition

Manifestation of schemia heart Disease 1.Angina pectoris 2. Myocardial infarction 3.Heart Failure and Arrhythmias 4.No obvious clinical manifestation

Manifestation of Ischemia Heart Disease 1.Angina Pectoris 2.MyocardialInfarction 3.Heart Failure and Arrhythmias 4.No obvious clinical manifestation

Acute coronary syndrome Account for more than 50%o Manifested with unstable angina pectoris, acute myocardial infarction (ST-segment elevate or non-ST-Segment elevate), cardiac shock

Acute coronary syndrome Account for more than 50% Manifested with unstable angina pectoris, acute myocardial infarction(ST-segment elevate or non-ST-segment elevate), cardiac shock

美国心血管病流行疯学 第一大死亡原因 1998年460,000人死于该病 每5个成年人中就有一个 收病率 每年约1,100,000人新发或复发冠心病,其中40 %死于该病 每年约有400,000新发稳定烈心绞痛病例和 150,000新发不稳定型心绞痛病例 目前,12,000,000人具有心梗和/或心绞痛史

• 第一大死亡原因 –1998年460,000人死于该病 –每5个成年人中就有一个 • 发病率 –每年约1,100,000人新发或复发冠心病，其中40 ％死于该病 –每年约有400,000新发稳定型心绞痛病例和 150,000新发不稳定型心绞痛病例 –目前，12,000,000人具有心梗和/或心绞痛史 美国心血管病流行病学

中国心血管病流行学 ◆20世纪后叶,在我国以心血管疾病为代表的慢 性疾病的发病率和死亡率日益增加 ◆目前佑计我国仅高血压病患者就近1亿人。心肌 梗死慶者200-300万人,死于冠心病的人数约30 万

中国心血管病流行病学 ◆20世纪后叶，在我国以心血管疾病为代表的慢 性疾病的 发病率和死亡率日益增加 ◆目前估计我国仅高血压病患者就近1亿人，心肌 梗死患者200－300万人，死于冠心病的人数约30 万

Atherosclerosis

Atherosclerosis

Obiective A. Understand the definition and classification of chd B Understand the pathophysiology of atherosclerosis C Grasping risk factors for coronary atherosclerosis and clinical features D Mastering diagnosis and prevention

A. Understand the definition and classification of CHD B.Understand the pathophysiology of atherosclerosis C.Grasping risk factors for coronary atherosclerosis and clinical features D.Mastering diagnosis and prevention Objective

Risk factors * Irreversible risk factors Age 2。 Male sex 3. Family History

Risk factors Irreversible risk factors 1. Age 2. Male sex 3. Family History