广州医科大学（广州医学院）：《病理学》课程教学资源（PPP课件，英文版）Chapter 2 Tissue repair

Chapter 2 Tissue repair Department ofpathology longjie

Chapter 2 Tissue repair Department of pathology longjie

Repair (修复) Would healing(创伤愈合)

Repair (修复） Would healing （创伤愈合）

Repair(修复) As cells and tissues are being injured, events that contain the damage and prepare the surviving cells to replicate are set into motion

Repair (修复） As cells and tissues are being injured, events that contain the damage and prepare the surviving cells to replicate are set into motion

Repair begins very early in the cell injury, and involves two processes 1. Regeneration(再生) 2. fibrosis (纤维性修复)

Repair begins very early in the cell injury, and involves two processes: 1. Regeneration (再生） 2. fibrosis （纤维性修复）

regeneration 再生 Regeneration of injured tissue by parenchymal cells of the same type

regeneration 再 生 Regeneration of injured tissue by parenchymal cells of the same type

types Physiological regeneration Pathological regeneration

types Physiological regeneration Pathological regeneration

Proliferative potential of different cell types Labile cells 不稳定细胞 Stable cells 稳定细胞 Permanent cells 永久性细胞

Proliferative potential of different cell types Labile cells Stable cells Permanent cells 不稳定细胞 稳定细胞 永久性细胞

Labile cells o Continuously dividing and dying ● Surface epl thelia stratified squamous surfaces cuboidal epithelia columnar epithlium transitional epithelium Hematopoietic cells

Labile cells ⚫ Continuously dividing and dying ⚫ Surface epithelia stratified squamous surfaces cuboidal epithelia columnar epithlium transitional epithelium ⚫ Hematopoietic cells

秒, N 腺上皮再生( Regeneration of glandular epithelia 腺体及其基底膜破坏,腺上皮增生,形成简单的腺体,进行修复。

Stable cells o Quiescent but can rapidly divide in response to injury Parenchymal of solid glandular tissues: liver, kidney, pancreas o Endothelial cells lining blood vessels ● fibroblast e Smooth muscle connective tissue

Stable cells ⚫ Quiescent but can rapidly divide in response to injury ⚫ Parenchymal of solid glandular tissues: liver, kidney, pancreas ⚫ Endothelial cells lining blood vessels ⚫ fibroblast ⚫ Smooth muscle connective tissue