复旦大学附属中山医院：《内科学》课程教学资源（PPT讲稿）白春学－呼吸衰竭 Respiratory Failure

Chapter 7 复里呼研斯 Respiratory Failure Bai chunxue Department of Respiratory disease Zhongshan Hospital Fudan University

1 Respiratory Failure Bai Chunxue Department of Respiratory disease Zhongshan Hospital Fudan University Chapter 7 复旦呼研所

Key Words 氯里呼研斯 Respiratory failure Acute respiratory distress syndrome (ARDS dyspnea Hypoxemia hypercapnia Respiratory Support Mechanical ventilation Positive end-expiratory pressure(PEEP)

2 Key Words ➢ Respiratory failure ➢ Acute respiratory distress syndrome(ARDS) ➢ dyspnea ➢ Hypoxemia ➢ hypercapnia ➢ Respiratory Support ➢ Mechanical ventilation ➢ Positive end-expiratory pressure (PEEP) 复旦呼研所

Chapter 7 复里呼研斯 Respiratory Failure Definition Type I、Ⅲ Respiratory Failure >Centrol\ Non-Centrol Respiratory Failure Acute chronic Respiratory Failure

3 Respiratory Failure Definition Chapter 7 ➢Type I、II Respiratory Failure ➢Centrol、 Non-Centrol Respiratory Failure ➢Acute & Chronic Respiratory Failure 复旦呼研所

复里呼研斯 ACUTEIN三 SPIRATORY FAILURE Bai chun Xue Department of Respiratory diseases Zhongshan Hospital

4 ACUTE RESPIRATORY FAILURE Bai Chun-Xue Department of Respiratory diseases Zhongshan Hospital 复旦呼研所

Definition 氯里呼研斯 respiratory dysfunction resulting in abnormalities of oxygenation or ventilation > impair or threaten the function of vital organs

5 ➢ respiratory dysfunction resulting in abnormalities of oxygenation or ventilation ➢ impair or threaten the function of vital organs Definition 复旦呼研所

Pathogeny 氯里呼研斯 Type l Type ll Parenchyma Airway Edema obstruction Vascular disease Chest wall Pleural Neuromuscular disease disease

6 Type I ➢ Parenchyma ➢ Edema ➢ Vascular disease ➢ Chest Wall & Pleural disease Type II ➢Airway obstruction ➢Neuromuscular disease Pathogeny 复旦呼研所

Clinical Findings 氯里呼研斯 hypoxemia Ventilation Diffusion Perfusion

7 hypoxemia Perfusion Diffusion Ventilation CO2 CO2 O2 O2 Clinical Findings 复旦呼研所

Clinical Findings 氯里呼研斯 hypercapnia CO

8 PA O 2 P ， ACO 2kPa) （ hypercapnia CO2 O2 Clinical Findings 复旦呼研所

Hypoxemia 氯里呼研斯 cyanosis, restlessness > confusion, anxiety, delirium tachypnea, tachycardia hypertension, cardiac arrhythmias tremor

9 ➢ cyanosis, restlessness ➢ confusion, anxiety, delirium ➢ tachypnea, tachycardia ➢ hypertension, cardiac arrhythmias ➢ tremor Hypoxemia 复旦呼研所

Hypercapnia 氯里呼研斯 > Dyspnea and headache peripheral and conjunctiva hyperemia hypertension, tachycardia, tachypnea >impaired consciousness papilledema, and asterixis

10 ➢ Dyspnea and headache ➢ peripheral and conjunctiva hyperemia ➢ hypertension, tachycardia,tachypnea ➢ impaired consciousness ➢ papilledema, and asterixis Hypercapnia 复旦呼研所