复旦大学附属中山医院：《内科学》课程教学资源（PPT讲稿）邹和健－风湿——血清阴性脊柱关节病（Serum RF negative spondylarthropathy）

模旦k d FUDAN UNIVERSITY 血清阴性脊柱关节病 (Serum rf negative spondylarthropathy Department of Internal Medicine Shanghai medical College Dr. He jian ZoU http://www

血清阴性脊柱关节病 （Serum RF negative spondylarthropathy） Department of Internal Medicine Shanghai Medical College Dr. Hejian ZOU http://www.hjzou.com

模旦k d FUDAN UNIVERSITY Clinical features) RF negtive low back pain and stiffness other joints enthesitis familial aggregation HLA-B27 related

【Clinical features】 RF negtive low back pain and stiffness other joints enthesitis familial aggregation HLA-B27 related

模旦k d FUDAN UNIVERSITY Classification】 Ankylosing spondylitis · Reiters syndrome Arthropathy of inflammatory bowel diseases Psoriatic arthritis Reactive arthritis Undifferentiated spondyloarthropathies

【Classification】 • Ankylosing spondylitis • Reiter’s syndrome • Arthropathy of inflammatory bowel diseases • Psoriatic arthritis • Reactive arthritis • Undifferentiated spondyloarthropathies

模旦k d FUDAN UNIVERSITY ( Criteria】 1. Low back pain at least 3 months' duration improved by exercise and not relieved by rest 2. Limitation of lumbarspine in sagittal and front planes 3. Chest expansion decreased relative to normal value for age and sex 4. Bilateral sacroiliitis grade 2-4 5. Unilateral sacroiliitis grade 3-4 Definite ankylosing spondylitis ifunilateralgrade 3 or 4, or bilateral grade 2-4 sacroiliitis and any clinial criterion

【 Criteria 】 1. Low back pain at least 3 months’ duration improved by exercise and not relieved by rest 2. Limitation of lumbar spine in sagittal and front planes 3. Chest expansion decreased relative to normal value for age and sex 4. Bilateral sacroiliitis grade 2-4 5. Unilateral sacroiliitis grade 3-4 Definite ankylosing spondylitis if unilateral grade 3 or 4, or bilateral grade 2-4 sacroiliitis and any clinial criterion

模旦k d FUDAN UNIVERSITY (Clinical manifestations) 1.Age:<40 2. Onset: insidiously 3. Pathology: enthesis 4. Clinical manifestation low back pain and stiffness arthritis ye disease cardiovascular disease

【Clinical manifestations】 1. Age: <40 2. Onset: insidiously 3. Pathology: enthesis 4. Clinical manifestation： low back pain and stiffness arthritis eye disease cardiovascular disease -------

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