麻省理工大学：《生物工程》教学讲义（英文版）lec 2 slides

Typical Length Scales in Biology IA lO microtubule DNA width width typical animal cell length of DNA in a chromosome prof. doyle 10 10 meters histone chromatin nucleus proteins width length of DNA contained in a typical human cell Central Doma DNA→8NA→ Proteins 55u5 4/10210.537

Images removed due to copyright considerations See Chapter 2, pp 70-72 in [Alberts-ECB Alberts, B, et al. Essential Cell Biology. New York: Garland Publishing, 1988

Images removed due to copyright considerations. See Chapter 2, pp. 70-72 in [Alberts-ECB]. Alberts, B., et al. Essential Cell Biology. New York: Garland Publishing, 1988

WHY No WE CARE ARoUS UEA“工飞 ERACTIONS E image removed due to copyright considerations See Figure 2-17 in [Alberts-ECB] Diagram of a pair of hypothetical proteins linked by two ionic bonds, one hydrogen bond and one large combination of hydrophobic and van der Walls interactions .MANY TO6ETHER sTRout G SPECLFLC TRAMSIENT/STA TISTIC AL ° MoLEL ULAR CON FoR MATI%owA, Titin ete…)

Image removed due to copyright considerations See page 101 in [Alberts-ECBI

Image removed due to copyright considerations. See page 101 in [Alberts-ECB]

Lipid bilayer ExtraceLlular Oligosaccharide Glycoprotein Periphera o Glycol pia Integral Hydrophobic core Hydrophillc intracelnfar model as a 2-D Elastic plate bending tension scaling arguments Comparison to Aspiration Experiments ac Kman R. L 410210537

Structure in Self-Assembled Peptides mages removed due to copyright considerations See Kamm, Nanoletters 2(2000)295-299 and Kamm, J Chem Physics 118(2003)389